Rapid cognitive screening of patients with substance use disorders.

Rapid cognitive screening of patients with substance use disorders.
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DOI:
10.1037/a0017260
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发表时间:
2009-10
影响因子:
2.3
通讯作者:
Weiss, Roger D.
Weiss, Roger D.
中科院分区:
医学3区
文献类型:
--
作者:
Copersino, Marc L.;Fals-Stewart, William;Fitzmaurice, Garrett;Schretlen, David J.;Sokoloff, Jody;Weiss, Roger D.

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到目前为止,还没有一个时间效率和资源意识的方法来识别物质使用障碍(SUD)患者的认知障碍。本研究评估的有效性,准确性和临床效用的一个简短的(10分钟)筛选工具,蒙特利尔认知评估(莫卡),在识别认知功能障碍的SUD患者。神经心理学评估组合筛选模块(NAB-SM)是一种45分钟的组合,对SUD患者中观察到的轻度至中度缺陷具有已知的敏感性,被用作确定莫卡的一致性、正确和不正确决策分类率以及标准相关有效性的参考标准。基于受试者操作特征(ROC)分析,莫卡的分类准确性很高,ROC曲线下面积= 0.86 [95%CI:0.75-0.97]。莫卡在识别认知功能障碍方面的敏感性(83.3%)和特异性(72.9%)也可接受。使用莫卡的临界值25,总体一致性为75.0%;机会校正一致性(kappa)为41.9%。这些研究结果表明,莫卡提供了一种时间效率和资源意识的方式来识别SUD患者的神经心理障碍,从而解决了成瘾治疗研究界的关键需求。
To date, there has not been a time-efficient and resource-conscious way to identify cognitive impairment in patients with substance use disorders (SUD). The present study assesses the validity, accuracy, and clinical utility of a brief (10 min) screening instrument, the Montreal Cognitive Assessment (MoCA), in identifying cognitive impairment among SUD patients. The Neuropsychological Assessment Battery-Screening Module (NAB-SM), a 45-minute battery with known sensitivity to the mild-to-moderate deficits observed in SUD patients, was used as the reference criterion for determining agreement, rates of correct and incorrect decision classifications, and criterion-related validity for the MoCA. Classification accuracy of the MoCA, based on receiver-operating characteristic (ROC) analysis, was strong, with an area under the ROC curve = 0.86 [95% CI: 0.75-0.97]. The MoCA also showed acceptable sensitivity (83.3%) and specificity (72.9%) for the identification of cognitive impairment. Using a cut-off of 25 on the MoCA, the overall agreement was 75.0%; chance-corrected agreement (kappa) was 41.9%. These findings indicate that the MoCA provides a time-efficient and resource-conscious way to identify SUD patients with neuropsychological impairment, thus addressing a critical need in the addiction treatment research community.
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