Towards time-of-flight PET with a semiconductor detector.
Towards time-of-flight PET with a semiconductor detector.
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DOI：
10.1088/1361-6560/aaaa4e
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发表时间：
2018-02-16
影响因子：
3.5
通讯作者：
Cherry SR
中科院分区：
文献类型：
--
作者：
Ariño-Estrada G;Mitchell GS;Kwon SI;Du J;Kim H;Cirignano LJ;Shah KS;Cherry SR
评估了使用切伦科夫光的可行性，该光由半导体TlBr中511 keV光子相互作用后的高能电子产生，以获得正电子发射断层扫描（PET）的快速定时信息。由于其高折射率，TlBr是相对良好的切伦科夫辐射体，并且由于其宽带隙，在大部分可见光谱中具有良好的光学透明度。将SiPM光电探测器耦合到TlBr（TlBr-SiPM）板产生TlBr-SiPM探测器和LFS参考探测器之间的620 ps FWHM的符合定时分辨率。通过基于TlBr-SiPM和参考检测器信号幅度应用高脉冲幅度切割，该值提高到430 ps FWHM。这些结果是半导体PET探测器有史以来最好的，已经接近飞行时间所需的性能。由于TlBr具有比目前用于PET扫描仪的常规闪烁探测器更高的阻止能力和更好的能量分辨率，具有快速定时能力的混合TlBr-SiPM探测器成为进一步开发的有趣选择。
The feasibility of using Cerenkov light, generated by energetic electrons following 511 keV photon interactions in the semiconductor TlBr, to obtain fast timing information for positron emission tomography (PET) was evaluated. Due to its high refractive index, TlBr is a relatively good Cerenkov radiator and with its wide bandgap, has good optical transparency across most of the visible spectrum. Coupling an SiPM photodetector to a slab of TlBr (TlBr-SiPM) yielded a coincidence timing resolution of 620 ps FWHM between the TlBr-SiPM detector and a LFS reference detector. This value improved to 430 ps FWHM by applying a high pulse amplitude cut based on the TlBr-SiPM and reference detector signal amplitudes. These results are the best ever achieved with a semiconductor PET detector and already approach the performance required for time-of-flight. As TlBr has higher stopping power and better energy resolution than the conventional scintillation detectors currently used in PET scanners, a hybrid TlBr-SiPM detector with fast timing capability becomes an interesting option for further development.
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影响因子：
1.3
作者：
Arino, G.;Chmeissani, M.;Uzun, D.
通讯作者：
Uzun, D.
DOI：
10.1109/tns.2016.2623807
发表时间：
2017-01
影响因子：
4.4
作者：
Groll A;Kim K;Bhatia H;Zhang JC;Wang JH;Shen ZM;Cai L;Dutta J;Li Q;Meng LJ
通讯作者：
Meng LJ
影响因子：
--
作者：
RODNEY, WS;MALITSON, IH
通讯作者：
MALITSON, IH
影响因子：
3.8
作者：
Somlai-Schweiger, I.;Ziegler, S. I.
通讯作者：
Ziegler, S. I.
影响因子：
2.4
作者：
Abbaszadeh, Shiva;Levin, Craig S.
通讯作者：
Levin, Craig S.