Effects of volatile anesthetics on cardiac sarcoplasmic reticulum as determined in intact cells.

Effects of volatile anesthetics on cardiac sarcoplasmic reticulum as determined in intact cells.
复制标题

在完整细胞中测定挥发性麻醉剂对心脏肌浆网的影响。

DOI:
10.1007/978-1-4684-5979-1_13
复制
发表时间:
1991
影响因子:
--
通讯作者:
Rice,RT
Rice,RT
中科院分区:
医学4区
文献类型:
--
作者:
Wheeler,DM;Katz,A;Rice,RT

文献摘要

参考文献

相似文献

虽然人们普遍认为挥发性麻醉剂氟烷、恩氟烷和异氟烷作用于心肌细胞的肌浆网(SR)和肌膜(SL),但尚不清楚这三种药物是否在这些部位具有相同的定性作用。在许多制剂中,已经证明异氟烷的负性肌力作用不如氟烷或恩氟烷。1 - 5最近已经证明,在等麻醉浓度下,这些药物对第二内向电流峰值的抑制程度相似。6 - 8这些药物对SR的影响不太容易测量,并且有证据表明氟烷和异氟烷的作用之间存在重大差异。9由于这些药物之间的负性肌力效力的差异似乎是它们在SR处的作用的结果,我们试图记录所有三种常用药剂在SR中的效果差异。
While it is generally agreed that the volatile anesthetics halothane, enflurane and isoflurane act at both the sarcoplasmic reticulum (SR) and sarcolemma (SL) in cardiac cells, it is less clear whether all three agents have the same qualitative effects at these sites. In many preparations, it has been demonstrated that isoflurane has a less potent negative inotropic effect than halothane or enflurane.1–5It has recently been demonstrated that at equi-anesthetic concentrations the agents produce a similar degree of depression of peak second inward current.6–8The effect of these agents at the SR is less readily measured, and evidence exists that there is a major difference between halothane’s and isoflurane’s action there.9Since it appeared that the differences in negative inotropic potency among these agents are a consequence of their actions at the SR, we sought to document differences in effect at the SR for all three commonly used agents.
酚类对再氧化微粒体结合细胞色素 b5 的刺激及其对脂肪酸去饱和的影响。
DOI: --
发表时间: 1971
期刊: Journal of Biochemistry (Tokyo)
影响因子: --
作者:
N. Oshino;R. Sato
通讯作者: R. Sato
哺乳动物细胞色素 b5 编码基因的合成、细菌表达和诱变。
DOI: 10.1073/pnas.83.24.9443
发表时间: 1986
影响因子: 11.1
作者:
BeckvonBodman,S;Schuler,MA;Jollie,DR;Sligar,SG
通讯作者: Sligar,SG
合成叶绿素内酯-和细菌叶绿素内酯-脱肌红蛋白复合物的溶液特性。
DOI: 10.1021/bi00529a033
发表时间: 1981
期刊: Biochemistry
影响因子: 2.9
作者:
Wright,KA;Boxer,SG
通讯作者: Boxer,SG
DOI: 10.1021/jo00224a075
发表时间: 1985
影响因子: 3.6
作者:
C. Chang;C. Sotiriou
通讯作者: C. Sotiriou
铁细胞色素 b5:根据核奥弗豪瑟效应测量和蛋白间与伙伴氧化还原蛋白接触的性质来分配丙酸血红素共振
DOI: 10.1021/ja00266a026
发表时间: 1986
影响因子: 15
作者:
S. McLachlan;G. N. Mar;E. Sletten
通讯作者: E. Sletten