Immunomodulation of nanoparticles in nanomedicine applications.

Immunomodulation of nanoparticles in nanomedicine applications.
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DOI:
10.1155/2014/426028
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发表时间:
2014
影响因子:
--
通讯作者:
Zhang Q
Zhang Q
中科院分区:
生物学3区
文献类型:
--
作者:
Jiao Q;Li L;Mu Q;Zhang Q

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Nanoparticles (NPs) have promising applications in medicine. Immune system is an important protective system to defend organisms from non-self matters. NPs interact with the immune system and modulate its function, leading to immunosuppression or immunostimulation. These modulating effects may bring benefits or danger. Compositions, sizes, and surface chemistry, and so forth, affect these immunomodulations. Here we give an overview of the relationship between the physicochemical properties of NPs, which are candidates to be applied in medicine, and their immunomodulation properties.
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