Real-time electronic adherence monitoring is feasible, comparable to unannounced pill counts, and acceptable.
Real-time electronic adherence monitoring is feasible, comparable to unannounced pill counts, and acceptable.
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DOI：
10.1007/s10461-011-9933-y
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发表时间：
2012-02
影响因子：
4.4
通讯作者：
Bangsberg, David R.
中科院分区：
文献类型：
--
作者：
Haberer, Jessica E.;Robbins, Gregory K.;Ybarra, Michele;Monk, Alexandra;Ragland, Kathleen;Weiser, Sheri D.;Johnson, Mallory O.;Bangsberg, David R.
第二代电子药物依从性监测器提供关于药瓶打开行为的实时数据。然而，可行性、有效性和可接受性尚未确定。Med-eMonitor是一种多隔室依从性设备，具有提醒和教育功能，可通过电话连接传输数据。使用Med-eMonitor（未调整和调整参与者确认的剂量）和未公布的药丸计数，在大约三个月内测量了52名参与者的每月依从性水平。在三个月期间之前和之后评估HIV RNA。确定Med-eMonitor的可接受性。超过92%的Med-eMonitor数据每天传输。未经通知的药丸数量与调整后的Med-eMonitor依从性显著相关（r=0.29，p=0.04）。HIV RNA与未公布的避孕药数量显著相关（r=-0.34，p=0.02），并与未调整的Med-eMonitor依从性显著相关（r=-0.26，p=0.07）。大多数（但不是全部）参与者喜欢使用Med-eMonitor。Med-eMonitor允许实时依从性监测和潜在干预，这对于延长治疗成功至关重要。
Second generation electronic medication adherence monitors provide real-time data on pill bottle opening behavior. Feasibility, validity, and acceptability, however, have not been established. Med-eMonitor is a multi-compartment adherence device with reminder and education capacity that transmits data through a telephone connection. Monthly adherence levels were measured for 52 participants over approximately three months using the Med-eMonitor (unadjusted and adjusted for participant confirmed dosing) and unannounced pill counts. HIV RNA was assessed before and after the three-month period. Acceptability of Med-eMonitor was determined. Over 92% of Med-eMonitor data was transmitted daily. Unannounced pill counts significantly correlated with adjusted Med-eMonitor adherence (r=0.29, p=0.04). HIV RNA significantly correlated with unannounced pill counts (r=−0.34, p=0.02), and trended toward a significant correlation with unadjusted Med-eMonitor adherence (r=−0.26; p=0.07). Most, but not all, participants liked using the Med-eMonitor. Med-eMonitor allows for real-time adherence monitoring and potentially intervention, which may be critical for prolonging treatment success.
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影响因子：
3.8
作者：
Bangsberg, DR;Perry, S;Moss, A
通讯作者：
Moss, A
影响因子：
4.6
作者：
Grossberg, Robert;Gross, Robert
通讯作者：
Gross, Robert
影响因子：
3.3
作者：
Drews, Frank A.;Picciano, Paul;Strayer, David L.
通讯作者：
Strayer, David L.
影响因子：
11.8
作者：
Petersen, Maya L.;Wang, Yue;Bangsberg, David R.
通讯作者：
Bangsberg, David R.
影响因子：
3.7
作者：
Parienti, Jean-Jacques;Das-Douglas, Moupali;Massari, Veronique;Guzman, David;Deeks, Steven G.;Verdon, Renaud;Bangsberg, David R.
通讯作者：
Bangsberg, David R.