Auditory brain stem responses in patients with human immunotropic virus infection of different stages.
Auditory brain stem responses in patients with human immunotropic virus infection of different stages.
复制标题
不同阶段人类免疫病毒感染患者的听觉脑干反应
作者：
H. Welkoborsky;K. Lowitzsch
对30名不同阶段的人类免疫病毒感染患者（26名男性，4名女性）进行了检查。 11 名患者有静脉注射病史。滥用药物，9名患者有治疗卢埃斯感染史，1名患者患有卡波西肉瘤。检查时，没有任何患者出现明显的机会性感染或急性脑炎。所有患者均接受了耳神经学检查，包括纯音测听、热量前庭测试和听觉脑干反应（ABR）记录。六名患者报告在过去 3 年内出现听力障碍。其中两人患有扁平感音神经性听力损失；在其他情况下，纯音听力测试显示高音听力损失并伴有负复张。 19 例 ABR 正常，与对照组的值相比，波 III 和 V 的潜伏期以及 I-V 峰间潜伏期显着延迟。 ABR 异常发现的频率与疾病的阶段无关。研究结果表明，听觉异常，更具体地说，ABR 异常通常发生在人类免疫病毒性疾病中。需要更多的研究来证明 ABR 是否适合监测治疗效果。
Thirty patients (26 men, 4 women) with human immunotropic virus infection of different stages were examined. Eleven patients had a history of i.v. drug abuse, nine patients had a history of treated lues infection, and one patient suffered from Kaposi's sarcoma. At the time of the examination, opportunistic infections or acute encephalitis were not apparent in any patient. All patients underwent otoneurological examinations, including pure-tone audiometry, caloric vestibular testing, and recording of the auditory brain stem responses (ABR). Six patients reported onset of hearing impairment during the last 3 yr. Two of them had flat sensorineural hearing loss; in the other cases, pure-tone audiometry showed high tone hearing loss with negative recruitment. ABRs were normal in 19 cases, with the latencies for waves III and V and for the I-V interpeak latency significantly delayed when compared to the values of the control group. The frequency of abnormal ABR findings did not correlate to the stage of the disease. The results of the study indicate that auditory and, more specifically, ABR abnormalities commonly occur in human immunotropic virus disease. More studies are necessary to prove whether the ABR is suitable to monitor therapeutic effects.
DOI：
10.1080/01947648809513542
发表时间：
1988-12
期刊：
The Journal of legal medicine
影响因子：
--
作者：
L. Prockop
通讯作者：
L. Prockop