Suppression of luteinizing hormone secretion is removed at late lactation in ovariectomized lactating rats.
Suppression of luteinizing hormone secretion is removed at late lactation in ovariectomized lactating rats.
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在切除卵巢的哺乳大鼠中，在哺乳后期，黄体生成素分泌的抑制作用被消除。
DOI：
10.1507/endocrj1954.34.709
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发表时间：
1987
期刊：
影响因子：
--
通讯作者：
A. Yokoyama
中科院分区：
文献类型：
--
作者：
K. Maeda;H. Tsukamura;A. Yokoyama
本文观察了哺乳刺激对哺乳期中后期(哺乳期第10天和第20天)大鼠搏动性黄体生成素(LH)分泌的影响。正常大鼠在哺乳期第10天或第20天的脉动性黄体生成素分泌受到强烈抑制，而黄体生成素的基线水平很低。去卵巢大鼠在哺乳期第10天与正常大鼠的基础值一样低，6只大鼠中有3只观察到搏动性的促黄体生成素分泌。第20天基础分泌量增加，6只大鼠中有5只出现脉冲性的黄体生成素分泌，每只大鼠的基础分泌量都有不同程度的变化。这些结果清楚地表明，正常大鼠在哺乳期第18-23天排卵时，其搏动性黄体生成素的分泌一直受到强烈的抑制，提示在哺乳期晚期，下丘脑-垂体水平的哺乳刺激对搏动性黄体生成素分泌的抑制被解除，而且这种抑制的时间因动物不同而不同。
The effect of the suckling stimulus on pulsatile luteinizing hormone (LH) secretion in mid- and late lactation (days 10 and 20 of lactation) in rats was examined. Pulsatile LH secretion was strongly suppressed on either day 10 or 20 of lactation in intact rats in which the baselines of LH secretion were kept very low. In ovariectomized rats the baseline was kept as low as was observed in intact rats on day 10 of lactation, and pulsatile LH secretion was observed in 3 out of 6 rats. On day 20 the baseline secretion increased and pulsatile LH secretion was observed in 5 out of 6 rats, and the baseline for each rat showed various levels. These results clearly indicate that the pulsatile LH secretion was strongly suppressed until ovulation occurred on day 18-23 of lactation in intact rats and suggest that suppression of pulsatile LH secretion by the suckling stimulus at the hypothalamo-pituitary level is removed in late lactation and the time of the removal varies from animal to animal.
催乳素在恒河猴（Macaca mulatta）哺乳期闭经中的作用。
影响因子：
3.6
作者：
Schallenberger,E;Richardson,DW;Knobil,E
通讯作者：
Knobil,E