Comparative bone tissue integration of nanostructured and microroughened dental implants.
Comparative bone tissue integration of nanostructured and microroughened dental implants.
复制标题
纳米结构和微粗糙化牙种植体的骨组织整合比较。
作者：
L. Salou;A. Hoornaert;J. Stanovici;S. Briand;G. Louarn;P. Layrolle
目的
目的是将纳米结构种植体的骨整合与广泛用于钛牙种植体的微表面进行比较。
材料与方法
具有光滑或微粗糙表面的商用钛牙种植体是纳米结构的。将植入物插入兔子的股骨髁中。 2周和4周后，进行组织形态计量学计算。
结果
在S-NANO（粗糙度：0.05 μm）和R-NANO（粗糙度：0.40 μm）表面均观察到直径为60 nm的纳米管。 MICRO 表面表现出典型的随机空腔（粗糙度：2.09 μm）。第 4 周时，R-NANO 的骨与种植体接触值显着高于 MICRO 表面，而第 2 周时没有观察到差异。
结论
总体而言，这项研究表明纳米结构表面改善的骨整合与 MICRO 相似或更高。
AIM
The aim was to compare osteointegration of nanostructured implants to a microsurface widely used for titanium dental implants.
MATERIALS & METHODS
Commercial titanium dental implants with smooth or microroughened surfaces were nanostructured. Implants were inserted into the femoral condyles of rabbits. After 2 and 4 weeks, histomorphometry calculation was performed.
RESULTS
Nanotubes measuring 60 nm in diameter were observed on both S-NANO (roughness: 0.05 μm) and R-NANO (roughness: 0.40 μm) surfaces. The MICRO surface exhibited typical random cavities (roughness: 2.09 μm). At 4 weeks, bone-to-implant contact values were significantly higher for the R-NANO than for the MICRO surface while no differences were observed at 2 weeks.
CONCLUSION
Overall, this study shows that the nanostructured surfaces improved osteointegration similar or higher than the MICRO.
影响因子：
11.8
作者：
McBeath, R;Pirone, DM;Chen, CS
通讯作者：
Chen, CS
影响因子：
41.2
作者：
Dalby, Matthew J.;Gadegaard, Nikolaj;Oreffo, Richard O. C.
通讯作者：
Oreffo, Richard O. C.