Dopamine and the interdependency of time perception and reward.

Dopamine and the interdependency of time perception and reward.
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多巴胺与时间知觉和奖赏的相互依赖性。

DOI:
10.1016/j.neubiorev.2021.02.030
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发表时间:
2021-06
影响因子:
8.2
通讯作者:
Shuler, Marshall G. Hussain
Shuler, Marshall G. Hussain
中科院分区:
医学1区
文献类型:
--
作者:
Fung, Bowen J.;Sutlief, Elissa;Shuler, Marshall G. Hussain

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时间是我们感知世界的基本维度,因此对人类行为的组织至关重要。包括最近光遗传学证据在内的大量研究表明,纹状体多巴胺是影响时间感知的关键因素。另一系列的文献表明多巴胺参与了奖励和动机过程。然而,这两个研究领域在很大程度上仍然是分开的,尽管神经生物学有重叠,而且有“当你玩得开心时,时间会过得很快”的格言。本文回顾了时间知觉与奖赏的相关文献,包括神经生物学和行为学研究。总之,这些提供了令人信服的支持的想法,时间知觉和奖励处理通过一个共同的多巴胺能机制相互作用。
Time is a fundamental dimension of our perception of the world and is therefore of critical importance to the organization of human behavior. A corpus of work — including recent optogenetic evidence — implicates striatal dopamine as a crucial factor influencing the perception of time. Another stream of literature implicates dopamine in reward and motivation processes. However, these two domains of research have remained largely separated, despite neurobiological overlap and the apothegmatic notion that “time flies when you’re having fun”. This article constitutes a review of the literature linking time perception and reward, including neurobiological and behavioral studies. Together, these provide compelling support for the idea that time perception and reward processing interact via a common dopaminergic mechanism.
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