Aortic root dimension changes during systole and diastole: evaluation with ECG-gated multidetector row computed tomography.

Aortic root dimension changes during systole and diastole: evaluation with ECG-gated multidetector row computed tomography.
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主动脉根维在收缩和舒张期间的变化:ECG门控多探测器行计算层析成像的评估。

DOI:
10.1007/s10554-011-9838-x
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发表时间:
2011-12
影响因子:
2.1
通讯作者:
Kluin, Jolanda
Kluin, Jolanda
中科院分区:
医学4区
文献类型:
--
作者:
de Heer, Linda M.;Budde, Ricardo P. J.;Mali, Willem P. Th. M.;de Vos, Alexander M.;van Herwerden, Lex A.;Kluin, Jolanda

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心脏搏动和主动脉顺应性可导致整个主动脉在整个心动周期内主动脉面积和直径的变化。在此之前,这些动态变化无法在主动脉根部(主动脉环、Valsalva窦和窦管交界处)建立。本研究的目的是利用ecg门控多排计算机断层扫描(MDCT)可视化和表征收缩期和舒张期主动脉根部尺寸的变化。对无主动脉根部疾病的受试者进行多层螺旋ct扫描分析。回顾性地,在收缩期(30-40%)和舒张期(70-75%)每10%的心脏周期进行心电图门控重建并分析。在主动脉根部的三个不同水平重建轴向平面。在每一层测量最大尺寸及其垂直腔尺寸。整个研究组的平均维度(n = 108,平均年龄56±13岁)在收缩期和舒张期之间没有显着差异。单个尺寸最大可达5毫米。然而,在- 5毫米(舒张尺寸大于收缩尺寸)和5毫米(反之亦然)之间存在差异。这种变异与性别、年龄、身高和体重无关。这项研究表明主动脉根部的尺寸有显著的个体动态变化。这些结果是高度不可预测的。大多数健康人的收缩期尺寸较大,但也有一些人的舒张期尺寸较大。
Cardiac pulsatility and aortic compliance may result in aortic area and diameter changes throughout the cardiac cycle in the entire aorta. Until this moment these dynamic changes could never be established in the aortic root (aortic annulus, sinuses of Valsalva and sinotubular junction). The aim of this study was to visualize and characterize the changes in aortic root dimensions during systole and diastole with ECG-gated multidetector row computed tomography (MDCT). MDCT scans of subjects without aortic root disease were analyzed. Retrospectively, ECG-gated reconstructions at each 10% of the cardiac cycle were made and analyzed during systole (30–40%) and diastole (70–75%). Axial planes were reconstructed at three different levels of the aortic root. At each level the maximal and its perpendicular luminal dimension were measured. The mean dimensions of the total study group (n = 108, mean age 56 ± 13 years) do not show any significant difference between systole and diastole. The individual dimensions vary up to 5 mm. However, the differences range between minus 5 mm (diastolic dimension is greater than systolic dimensions) and 5 mm (vice versa). This variability is independent of gender, age, height and weight. This study demonstrated a significant individual dynamic change in the dimensions of the aortic root. These results are highly unpredictable. Most of the healthy subjects have larger systolic dimensions, however, some do have larger diastolic dimensions.
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