Operation and Performance of a Mass-Selective Cryogenic Linear Ion Trap.

Operation and Performance of a Mass-Selective Cryogenic Linear Ion Trap.
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DOI:
10.1007/s13361-018-2026-7
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发表时间:
2018-11
影响因子:
3.2
通讯作者:
Polfer NC
Polfer NC
中科院分区:
化学3区
文献类型:
--
作者:
Tesler LF;Cismesia AP;Bell MR;Bailey LS;Polfer NC

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我们报道了一种低温二维线性离子阱(cryoLIT)的性能,它在17 - 295K的温度范围内具有质量选择性。随着cryoLIT被冷却,在质量不稳定扫描期间的引出电压降低,这导致相对于室温向更低的质荷比(m/z)发生有效的质量偏移。这归因于热收缩引起的离子阱半径减小。此外,cryoLIT每天都能产生可重复的质谱,并且能够对脆弱的带有N₂标记的离子进行存储波形逆傅里叶变换(SWIFT)质量隔离,以用于无背景的红外解离光谱分析。
We report on the performance of a cryogenic 2D linear ion trap (cryoLIT) that is shown to be mass-selective in the temperature range of 17 – 295K. As the cryoLIT is cooled, the ejection voltages during the mass instability scan decrease, which results in an effective mass shift to lower m/z relative to room temperature. This is attributed to a decrease in trap radius caused by thermal contraction. Additionally, the cryoLIT generates reproducible mass spectra from day-to-day, and is capable of performing stored waveform inverse Fourier transform (SWIFT) mass isolation of fragile N2-tagged ions for the purpose of background-free infrared dissociation spectroscopy.
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