Multiple-point magnetic resonance acoustic radiation force imaging.
Multiple-point magnetic resonance acoustic radiation force imaging.
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DOI：
10.1002/mrm.27477
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发表时间：
2019-03
影响因子：
3.3
通讯作者：
Parker DL
中科院分区：
文献类型：
--
作者：
Odéen H;de Bever J;Hofstetter LW;Parker DL
旨在实现和评价一种高效的多点MR声辐射力成像脉冲序列，该脉冲序列可以使用聚焦超声（FUS）辐射力对组织位移进行体积测量并评价组织刚度。在2D和3D采集模式下，将双极运动编码梯度添加到梯度召回回波分段EPI脉冲序列中。在TR水平上将多个FUS-ON图像（FUS功率> 0 W）与单个FUS-OFF图像（FUS功率= 0 W）交错，从而能够同时测量体积组织位移（通过从FUS-ON图像中复减FUS-OFF图像）和质子共振频移MR测温（从OFF图像）。效率改进包括部分傅立叶采集、并行成像以及将多达4个不同的位移位置编码到单个图像中。实验在均质和双刚度体模和离体猪脑中进行。在体模中，16点多点磁共振声辐射力成像图可以在5 s至10 s内获得一个2D切片，60 s内获得一个3D体积，使用并行成像和编码2个位移位置/图像。在离体猪脑中，16点多点磁共振声辐射力成像图可以在20 s内获得一个3D体积，使用部分傅立叶和并行成像和编码4个位移位置/图像。在1项实验中，观察到FUS消融后离体脑中的组织位移减少约22%。利用所描述的效率改进，可以在临床上可接受的时间内采集体积多点磁共振声辐射力成像图，同时具有质子共振频移MR测温图。
To implement and evaluate an efficient multiple-point MR acoustic radiation force imaging pulse sequence that can volumetrically measure tissue displacement and evaluate tissue stiffness using focused ultrasound (FUS) radiation force. Bipolar motion-encoding gradients were added to a gradient-recalled echo segmented EPI pulse sequence with both 2D and 3D acquisition modes. Multiple FUS-ON images (FUS power > 0 W) were interleaved with a single FUS-OFF image (FUS power = 0 W) on the TR level, enabling simultaneous measurements of volumetric tissue displacement (by complex subtraction of the FUS-OFF image from the FUS-ON images) and proton resonance frequency shift MR thermometry (from the OFF image). Efficiency improvements included partial Fourier acquisition, parallel imaging, and encoding up to 4 different displacement positions into a single image. Experiments were performed in homogenous and dual-stiffness phantoms, and in ex vivo porcine brain. In phantoms, 16-point multiple-point magnetic resonance acoustic radiation force imaging maps could be acquired in 5 s to 10 s for a 2D slice, and 60 s for a 3D volume, using parallel imaging and encoding 2 displacement positions/image. In ex vivo porcine brain, 16-point multiple-point magnetic resonance acoustic radiation force imaging maps could be acquired in 20 s for a 3D volume, using partial Fourier and parallel imaging and encoding 4 displacement positions/image. In 1 experiment it was observed that tissue displacement in ex vivo brain decreased by approximately 22% following FUS ablation. With the described efficiency improvements it is possible to acquire volumetric multiple-point magnetic resonance acoustic radiation force imaging maps, with simultaneous proton resonance frequency shift MR thermometry maps, in clinically acceptable times.
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DOI：
10.1186/2050-5736-1-8
发表时间：
2013
期刊：
Journal of therapeutic ultrasound
影响因子：
--
作者：
Hijnen NM;Elevelt A;Pikkemaat J;Bos C;Bartels LW;Grüll H
通讯作者：
Grüll H
DOI：
10.1186/s40349-015-0030-y
发表时间：
2015
期刊：
Journal of therapeutic ultrasound
影响因子：
--
作者：
Farrer AI;Odéen H;de Bever J;Coats B;Parker DL;Payne A;Christensen DA
通讯作者：
Christensen DA
影响因子：
3.3
作者：
de Bever, Joshua T.;Odeen, Henrik;Parker, Dennis L.
通讯作者：
Parker, Dennis L.
影响因子：
4.4
作者：
Bitton, Rachel R.;Kaye, Elena;Pauly, Kim Butts
通讯作者：
Pauly, Kim Butts
影响因子：
3.8
作者：
Hertzberg, Y.;Volovick, A.;Navon, G.
通讯作者：
Navon, G.