Nutritional Epidemiologic Survey of the Relationship between Satsuma Mandarin Intake and the Risk for Lifestyle-related Diseases : Mikkabi Prospective Cohort Study
Nutritional Epidemiologic Survey of the Relationship between Satsuma Mandarin Intake and the Risk for Lifestyle-related Diseases : Mikkabi Prospective Cohort Study
复制标题
蜜柑摄入量与生活方式相关疾病风险之间关系的营养流行病学调查：Mikkabi 前瞻性队列研究
DOI：
--
复制
发表时间：
2014
期刊：
影响因子：
--
通讯作者：
M. Sugiura
中科院分区：
文献类型：
--
作者：
M. Sugiura
抗氧化微量营养素，如维生素和类胡萝卜素，在水果和蔬菜中大量存在，已知有助于身体防御活性氧。最近的许多流行病学研究表明，饮食中大量食用富含类胡萝卜素或产生高血清类胡萝卜素浓度的水果和蔬菜，可降低某些癌症、糖尿病和心血管疾病的风险。这些流行病学研究表明，抗氧化类胡萝卜素对几种与生活方式有关的疾病具有保护作用。-隐黄素是一种类胡萝卜素，尤其在日本大量生产的柑橘（Citrus unshiu Marc.）水果中发现。我们的营养流行病学调查，Mikkabi研究，利用了来自日本静冈县Mikkabi镇居民健康检查的数据。在这项调查中，我们测量了血清β -隐黄质作为一种特定的生物标志物，以估计日本柑橘的消费量。Mikkabi研究的横断面分析表明，血清β-隐黄质与动脉粥样硬化、胰岛素抵抗、肝功能障碍、代谢综合征、低骨密度和氧化应激的风险呈负相关。在这一章中，最近的流行病学研究之间的关系血清-隐黄质和几种生活方式相关疾病的风险进行综述。（2014年5月8日接受）
Antioxidant micronutrients such as vitamins and carotenoids exist in abundance in fruits and vegetables and are known to contribute to the body’s defense against reactive oxygen species. Numerous recent epidemiologic studies have demonstrated that a high dietary consumption of fruits and vegetables rich in carotenoids or producing high serum carotenoid concentrations results in a decreased risk for certain cancers, diabetes, and cardiovascular disease. These epidemiologic studies have suggested that antioxidant carotenoids exert a protective effect against several lifestyle-related diseases. Beta-cryptoxanthin is a carotenoid pigment particularly found in Japanese mandarin (Citrus unshiu Marc.) fruit, which is heavily produced in Japan. Our nutritional epidemiologic survey, the Mikkabi Study, utilized data derived from health examinations involving inhabitants of the town of Mikkabi in Shizuoka, Japan. In this survey, we measured serum beta-cryptoxanthin as a specific bio-marker to estimate the consumption of Japanese mandarin fruit. The cross-sectional analyses of the Mikkabi Study indicated inverse associations between serum β-cryptoxanthin and the risk for atherosclerosis, insulin resistance, liver dysfunction, metabolic syndrome, low bone mineral density and oxidative stress. In this chapter, recent epidemiologic studies of the association between serum beta-cryptoxanthin and the risk for several lifestyle-related diseases are reviewed. (Accepted May 8, 2014)
DOI：
--
发表时间：
2003-09
期刊：
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
影响因子：
--
作者：
Jian-Min Yuan;D. Stram;Kazuko Arakawa;Hin‐Peng Lee;Mimi C. Yu
通讯作者：
Jian-Min Yuan;D. Stram;Kazuko Arakawa;Hin‐Peng Lee;Mimi C. Yu
影响因子：
158.5
作者：
Omenn, GS;Goodman, GE;Hammar, S
通讯作者：
Hammar, S
DOI：
10.1056/nejm199404143301501
发表时间：
1994-04-14
期刊：
The New England journal of medicine
影响因子：
--
作者：
通讯作者：
--