Persistent pain in postmastectomy patients: comparison of psychophysical, medical, surgical, and psychosocial characteristics between patients with and without pain.
Persistent pain in postmastectomy patients: comparison of psychophysical, medical, surgical, and psychosocial characteristics between patients with and without pain.
复制标题
DOI：
10.1016/j.pain.2012.11.015
复制
发表时间：
2013-05
期刊：
影响因子：
7.4
通讯作者：
Belfer I
中科院分区：
文献类型：
--
作者：
Schreiber KL;Martel MO;Shnol H;Shaffer JR;Greco C;Viray N;Taylor LN;McLaughlin M;Brufsky A;Ahrendt G;Bovbjerg D;Edwards RR;Belfer I
Persistent postmastectomy pain (PPMP) is a major individual and public health problem. Increasingly, psychosocial factors such as anxiety and catastrophizing are being revealed as crucial contributors to individual differences in pain processing and outcomes. Furthermore, differences in patients’ responses to standardized quantitative sensory testing (QST) may aid in the discernment of who is at risk for acute and chronic pain after surgery. However, characterization of the variables that differentiate those with PPMP from those whose acute postoperative pain resolves is currently incomplete. The purpose of this study was to investigate important surgical, treatment-related, demographic, psychophysical, and psychosocial factors associated with PPMP by comparing PPMP cases with PPMP-free controls. Pain was assessed using the breast cancer pain questionnaire to determine the presence and extent of PPMP. Psychosocial and demographic information were gathered via phone interview, and women underwent a QST session. Consistent with most prior research, surgical and disease-related variables did not differ significantly between cases and controls. Furthermore, treatment with radiation, chemotherapy, or hormone therapy was also not more common among those with PPMP. In contrast, women with PPMP did show elevated levels of distress-related psychosocial factors such as anxiety, depression, catastrophizing, and somatization. Finally, QST in nonsurgical body areas revealed increased sensitivity to mechanical stimulation among PPMP cases, while thermal pain responses were not different between the groups. These findings suggest that an individual’s psychophysical and psychosocial profile may be more strongly related to PPMP than their surgical treatment.
登录
查看更多内容
影响因子：
5
作者：
COHEN, S;KAMARCK, T;MERMELSTEIN, R
通讯作者：
MERMELSTEIN, R
影响因子：
7.4
作者：
Geisser, ME;Casey, KL;Crofford, LJ
通讯作者：
Crofford, LJ
影响因子：
7.4
作者：
Bisgaard, T;Klarskov, B;Kehlet, H
通讯作者：
Kehlet, H
影响因子：
120.7
作者：
Gartner, Rune;Jensen, Maj-Britt;Kehlet, Henrik
通讯作者：
Kehlet, Henrik
影响因子：
3.1
作者：
Fecho, Karamarie;Miller, Natalie R.;Blau, William S.
通讯作者：
Blau, William S.