COVID-19 Antibody Tests: A Valuable Public Health Tool with Limited Relevance to Individuals.
COVID-19 Antibody Tests: A Valuable Public Health Tool with Limited Relevance to Individuals.
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DOI：
10.1016/j.tim.2020.11.002
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发表时间：
2021-03
影响因子：
15.9
通讯作者：
Gronvall GK
中科院分区：
文献类型：
--
作者：
West R;Kobokovich A;Connell N;Gronvall GK
用于检测严重急性呼吸综合征冠状病毒2（SARS-CoV-2）既往感染的抗体检测在公共卫生决策中有许多用途，但需求主要来自个人消费者。本文综述了抗体检测的个体相关性：检测既往感染的准确性，过去的SARS-CoV-2感染目前可以推断未来的免疫力或可能的医学后遗症，以及抗体检测对疫苗选择和医学筛查的潜在重要性。鉴于抗体检测的不确定性（质量、准确度、阳性预测值）以及这些检测在免疫学上可能表明的情况（抗体的持久性和防止再感染的必要性），血清阳性检测结果不应用于为个人决策提供信息，抗体检测目前仍应是公共卫生的一种工具。
Antibody tests for detecting past infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have many uses for public health decision making, but demand has largely come from individual consumers. This review focuses on the individual relevance of antibody tests: their accuracy in detecting prior infection, what past SARS-CoV-2 infection can currently infer about future immunity or possible medical sequelae, and the potential future importance of antibody tests for vaccine selection and medical screening. Given uncertainty about the antibody tests (quality, accuracy level, positive predictive value) and what those tests might indicate immunologically (durability of antibodies and necessity for protection from reinfection), seropositive test results should not be used to inform individual decision making, and antibody testing should remain a tool of public health at this time.
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影响因子：
56.9
作者：
Chandrashekar, Abishek;Liu, Jinyan;Barouch, Dan H.
通讯作者：
Barouch, Dan H.
影响因子：
1
作者：
Demertzis, Zachary D.;Dagher, Carina;Suleyman, Geehan
通讯作者：
Suleyman, Geehan
影响因子：
33.9
作者：
Chow, Nancy;Fleming-Dutra, Katherine;Ussery, Emily
通讯作者：
Ussery, Emily
影响因子：
158.5
作者：
Feldstein, Leora R.;Rose, Erica B.;Randolph, Adrienne G.
通讯作者：
Randolph, Adrienne G.
DOI：
10.1136/bmj.m3939
发表时间：
2020-10-22
期刊：
BMJ (Clinical research ed.)
影响因子：
--
作者：
Agarwal A;Mukherjee A;Kumar G;Chatterjee P;Bhatnagar T;Malhotra P;PLACID Trial Collaborators
通讯作者：
PLACID Trial Collaborators