Gastroesophageal reflux disease in obese patients: the role of obesity in management.

Gastroesophageal reflux disease in obese patients: the role of obesity in management.
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肥胖患者的胃食管反流病:肥胖在治疗中的作用。

DOI:
10.1111/j.1442-2050.2006.00540.x
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发表时间:
2006
期刊:
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
影响因子:
--
通讯作者:
S. G. Houghton
S. G. Houghton
中科院分区:
--
文献类型:
--
作者:
M. Kendrick;S. G. Houghton

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胃食道反流病(GERD)在肥胖患者中很常见。由于肥胖的流行,肥胖在GERD的病因、管理和治疗结果中的意义变得越来越重要。同时患有肥胖症和GERD的患者的患病率越来越高,这需要评估GERD及其症状的适当手术治疗。随着减肥和解决与体重相关的发病率(包括GERD)的其他优势,减肥手术应该成为医学上复杂肥胖患者的首选手术。体重指数(BMI)为30-35公斤/平方米且无其他实质性体重相关合并症的低肥胖类别患者应立即考虑胃底折叠术和减肥手术,根据患者的具体情况和未来的影响量身定做最佳治疗方法。被归类为超重但不肥胖的患者(BMI<30)可能最好采用胃底折叠术;然而,目前还没有随机试验将胃底折叠术与目前的抗反流减肥手术进行比较。
Gastroesophageal reflux disease (GERD) is common in obese patients. The implications of obesity in the etiology, management and outcomes in treatment for GERD have become increasingly important due to an epidemic of obesity. The increasing prevalence of patients with both obesity and GERD merits evaluation of the appropriate surgical intervention for GERD and its symptoms. With the additional advantages of weight loss and resolution of weight-related morbidity (including GERD) bariatric procedures should be the procedure of choice in patients with medically complicated obesity. Patients in lower obesity classes with body mass indices (BMI) of 30-35 kg/m2 without other substantive weight-related comorbidity should prompt consideration of both fundoplication and bariatric procedures, tailoring the best approach based on the specific patient and future implications. Patients classified as overweight but not obese (BMI < 30) are likely best treated with fundoplication; however, no randomized trials comparing fundoplication with the current antireflux bariatric procedures exist.
DOI: 10.1056/nejm199903183401101
发表时间: 1999-03-18
影响因子: 158.5
作者:
Lagergren, J;Bergström, R;Nyrén, O
通讯作者: Nyrén, O
DOI: 10.1016/s0002-9343(99)00121-7
发表时间: 1999-06-01
影响因子: 5.9
作者:
Locke, GR;Talley, NJ;Melton, LJ
通讯作者: Melton, LJ