Allen Brain Atlas: an integrated spatio-temporal portal for exploring the central nervous system.

Allen Brain Atlas: an integrated spatio-temporal portal for exploring the central nervous system.
复制标题

DOI:
10.1093/nar/gks1042
复制
发表时间:
2013-01
影响因子:
14.9
通讯作者:
Dang C
Dang C
中科院分区:
生物学2区
文献类型:
--
作者:
Sunkin SM;Ng L;Lau C;Dolbeare T;Gilbert TL;Thompson CL;Hawrylycz M;Dang C

文献摘要

参考文献

被引文献

相似文献

Allen Brain Atlas (http://www.brain-map.org)提供了一个独特的在线公共资源,整合了广泛的基因表达数据、连接数据和神经解剖学信息,以及强大的搜索和查看工具,用于小鼠、人类和非人类灵长类动物的成年和发育中的大脑。在这里,我们回顾了Allen Brain Atlas的可用资源,描述了每种产品和数据类型[如原位杂交(ISH)和支持组织学,微阵列,RNA测序,参考地图集,投影测绘和磁共振成像]。此外,还描述了web应用程序中标准化和独特的功能,使用户能够搜索和挖掘各种数据集。功能包括简单和复杂的基因搜索方法,比色法和荧光ISH图像查看器,ISH图形显示,微阵列和RNA测序数据,用于解剖和基因表达3D导航的Brain Explorer软件,以及交互式参考图谱查看器。此外,跨数据集搜索使用户能够同时查询多个Allen Brain Atlas数据集。所有的Allen Brain Atlas资源都可以通过Allen Brain Atlas数据门户访问。
The Allen Brain Atlas (http://www.brain-map.org) provides a unique online public resource integrating extensive gene expression data, connectivity data and neuroanatomical information with powerful search and viewing tools for the adult and developing brain in mouse, human and non-human primate. Here, we review the resources available at the Allen Brain Atlas, describing each product and data type [such as in situ hybridization (ISH) and supporting histology, microarray, RNA sequencing, reference atlases, projection mapping and magnetic resonance imaging]. In addition, standardized and unique features in the web applications are described that enable users to search and mine the various data sets. Features include both simple and sophisticated methods for gene searches, colorimetric and fluorescent ISH image viewers, graphical displays of ISH, microarray and RNA sequencing data, Brain Explorer software for 3D navigation of anatomy and gene expression, and an interactive reference atlas viewer. In addition, cross data set searches enable users to query multiple Allen Brain Atlas data sets simultaneously. All of the Allen Brain Atlas resources can be accessed through the Allen Brain Atlas data portal.
DOI: 10.1186/1471-2105-9-153
发表时间: 2008-03-18
期刊: BMC BIOINFORMATICS
影响因子: 3
作者:
Lau, Christopher;Ng, Lydia;Hawrylycz, Mike
通讯作者: Hawrylycz, Mike
DOI: 10.1073/pnas.1003732107
发表时间: 2010-11-02
影响因子: 11.1
作者:
Morris, John A.;Royall, Joshua J.;Jones, Allan R.
通讯作者: Jones, Allan R.
DOI: 10.1038/nn.2281
发表时间: 2009-03-01
影响因子: 25
作者:
Ng, Lydia;Bernard, Amy;Hawrylycz, Michael
通讯作者: Hawrylycz, Michael
DOI: 10.1186/1756-0500-5-370
发表时间: 2012-07-23
期刊: BMC research notes
影响因子: 1.8
作者:
Klomp JA;Furge KA
通讯作者: Furge KA
DOI: 10.1038/nn.2467
发表时间: 2010-01
影响因子: 25
作者:
Madisen L;Zwingman TA;Sunkin SM;Oh SW;Zariwala HA;Gu H;Ng LL;Palmiter RD;Hawrylycz MJ;Jones AR;Lein ES;Zeng H
通讯作者: Zeng H