Common practices among consistently high-performing in vitro fertilization programs in the United States: 10-year update.
Common practices among consistently high-performing in vitro fertilization programs in the United States: 10-year update.
复制标题
DOI：
10.1016/j.fertnstert.2021.09.010
复制
发表时间：
2022-01
影响因子：
6.7
通讯作者：
Van Voorhis BJ
中科院分区：
文献类型：
--
作者：
Knudtson JF;Robinson RD;Sparks AE;Hill MJ;Chang TA;Van Voorhis BJ
评估高绩效生育诊所临床和实验室实践的异同。选定项目的横断面问卷研究 进行体外受精 (IVF) 的学术和私人生育实践 13 个 IVF 项目每年至少进行 100 个周期，并且连续两年具有较高的累积单胎分娩率。一项全面的调查 临床和实验室 IVF 实践 尽管顶级项目的临床实践的许多领域有所不同，但仍观察到一些共同点。所有计划均使用 FSH 和 LH 组合进行 IVF 刺激、冷冻胚胎移植周期中的肌内黄体酮、超声引导胚胎移植以及 IVF 周期开始前所需的精液分析。常见的实验室实践包括囊胚阶段胚胎的玻璃化冷冻、采用正压和 HEPA 过滤进行空气质量控制、使用培养箱气体过滤器、在加热显微镜台上工作以及在低氧环境中培养胚胎（最常见的是在台式培养箱中）。高性能体外受精项目在临床和实验室实践中的一些一致性领域被注意到，这可能有助于其成功。高性能诊所专注于单例分娩。随着 IVF 领域的快速发展，我们必须分享最佳实践，以努力改善所有诊所的治疗结果，造福患者。
To evaluate similarities and differences in clinical and laboratory practices among high-performing fertility clinics. Cross-sectional questionnaire study of selected programs Academic and private fertility practices performing in vitro fertilization (IVF) Thirteen IVF programs performing at least 100 cycles a year and having high cumulative singleton delivery rates for two years. A comprehensive survey Clinical and Laboratory IVF practices Although many areas of clinical practice vary among top programs some commonalities were observed. All programs use a combination of FSH and LH for IVF stimulation, intramuscular progesterone in frozen embryo transfer cycles, ultrasound guided embryo transfers, and a required semen analysis prior to IVF cycle start. Common laboratory practices include vitrification of embryos at the blastocyst stage, air quality control with positive air pressure and HEPA filtration, use of incubator gas filters, working on heated microscope stages, and incubating embryos in a low oxygen environment, most often in benchtop incubators. Some areas of consistency in clinical and laboratory practices were noted among high-performing IVF programs that are likely contributing to their success. High performing clinics are focused on singleton deliveries. As the field of IVF is rapidly evolving, it is imperative that we share best practices in an effort to improve outcomes from all clinics for the good of our patients.
登录
查看更多内容
影响因子：
6.7
作者：
Penzias, Alan;Bendikson, Kristin;Vernon, Michael
通讯作者：
Vernon, Michael
影响因子：
3.1
作者：
Munch, Erika M.;Sparks, Amy E.;Van Voorhis, Bradley J.
通讯作者：
Van Voorhis, Bradley J.
影响因子：
6.7
作者：
Hill, Micah J.;Healy, Mae Wu;Patounakis, George
通讯作者：
Patounakis, George
影响因子：
6.7
作者：
Penzias, Alan;Azziz, Ricardo;Yauger, Belinda
通讯作者：
Yauger, Belinda
影响因子：
6.7
作者：
Fabozzi, Gemma;Cimadomo, Danilo;Rienzi, Laura
通讯作者：
Rienzi, Laura