The Effect of Prolonged Stimulation of Salivary Flow on Bacterial Reactive Factors
The Effect of Prolonged Stimulation of Salivary Flow on Bacterial Reactive Factors
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长期刺激唾液流对细菌反应因子的影响
DOI：
10.1177/00220345830620030301
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发表时间：
1983
影响因子：
7.6
通讯作者：
J. Ebersole
中科院分区：
文献类型：
--
作者：
S. Kashket;K. Guilmette;J. Ebersole
长时间刺激唾液流会导致某些细菌聚集因子和菌株特异性抗体的浓度发生重大变化。血链球菌菌株的聚集活性迅速降低，而变形链球菌的三种菌株的活性保持不变，另外两种菌株的活性增加了几倍。结果与唾液蛋白和钙的变化无关。三种变形链球菌菌株的 IgA 和特异性 IgA 抗体浓度随着持续刺激而逐渐降低。腮腺、颌下唾液和全唾液也获得了类似的结果。这些发现表明，不同细菌反应物质从唾液腺的释放速率通常遵循独立的过程，此外，这些物质的反应范围随流速而变化。这种变化可能反映在菌斑的细菌组成上。
Prolonged stimulation of salivary flow leads to major changes in the concentrations of certain bacterial aggregating factors and strain-specific antibodies. Aggregating activity for a strain of Streptococcus sanguis was reduced rapidly, while activities for three strains of S. mutans remained unchanged, and activities for two other strains increased several-fold. The results were independent of changes in salivary protein and calcium. Concentrations of IgA and specific IgA antibodies for three S. mutans strains decreased progressively with continued stimulation. Similar results were obtained with parotid, submandibular, and whole saliva. These findings indicate that the rates of release of the different bacterial reactive substances from the salivary glands often follow independent courses and, furthermore, that the spectrum of reactivities of these substances changes with flow rate. Such changes may be reflected in the bacterial composition of plaque.
用于测量伴放线放线杆菌血清抗体的 ELISA。
影响因子：
3.5
作者：
Ebersole,JL;Frey,DE;Taubman,MA;Smith,DJ
通讯作者：
Smith,DJ