Vitamin D and calcium intake in relation to risk of endometrial cancer: a systematic review of the literature.
Vitamin D and calcium intake in relation to risk of endometrial cancer: a systematic review of the literature.
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维生素 D 和钙摄入量与子宫内膜癌风险的关系：文献的系统回顾。
DOI：
10.1016/j.ypmed.2007.11.010
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发表时间：
2008
影响因子：
5.1
通讯作者：
Kushi,LawrenceH
中科院分区：
文献类型：
--
作者：
McCullough,MarjorieL;Bandera,ElisaV;Moore,DirkF;Kushi,LawrenceH
OBJECTIVEIn response to a recent ecologic study of UV exposure and endometrial cancer incidence, we present the epidemiologic evidence on the relation between intake of vitamin D and its metabolically related nutrient, calcium, and the occurrence of endometrial cancer.METHODSWe conducted a systematic literature review and meta-analysis of vitamin D and calcium in relation to endometrial cancer, including peer-reviewed manuscripts published up to May 2007. Random and fixed effects summary estimates were computed.RESULTSPooled analyses of the three case-control studies of dietary vitamin D and endometrial cancer uncovered heterogeneous results that were not significant in random or fixed effects analyses. Cut-points for the highest vitamin D intakes ranged from >244 to >476 IU/day. Qualitatively similar findings were observed for dietary calcium. Only two studies provided estimates for calcium supplements (random effects OR=0.62, 95% CI 0.39–0.99; fixed effects OR=0.62, 95% CI 0.42–0.93, for top vs. bottom category, p for heterogeneity=0.25).CONCLUSIONSThe limited epidemiological evidence suggests no relation between endometrial cancer in the ranges of dietary vitamin D examined, and suggests a possible inverse association for calcium from supplements. Prospective studies, ideally including plasma 25(OH) D to estimate vitamin D input from diet and sun exposure, are needed to further explore these hypotheses.
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DOI：
--
发表时间：
1987
期刊：
Analytical and quantitative cytology and histology
影响因子：
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作者：
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DOI：
--
发表时间：
1983
期刊：
Journal of Reproduction and Fertility
影响因子：
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作者：
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G. Cooper
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DOI：
--
发表时间：
1974
期刊：
Journal of Ultrastructure Research
影响因子：
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作者：
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David Devorkin
公羊精子细胞的核重组。
DOI：
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发表时间：
1979
期刊：
Journal of Ultrastructure Research
影响因子：
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作者：
M. Loir;J. Courtens
通讯作者：
J. Courtens