The costs of depression.

The costs of depression.
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DOI:
10.1016/j.psc.2011.11.005
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发表时间:
2012-03
影响因子:
1.7
通讯作者:
Kessler, Ronald C.
Kessler, Ronald C.
中科院分区:
医学3区
文献类型:
--
作者:
Kessler, Ronald C.

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数据审查的社会成本的重性抑郁症(MDD)。早发性抑郁症被发现预测随后的角色转换中的困难,包括低教育程度,青少年生育的高风险,婚姻破裂和不稳定的就业。在具有特定社会和生产角色的人群中,MDD被发现预测角色功能的显著下降(例如,婚姻质量低、工作表现差、收入低)。MDD还与多种慢性身体疾病的发作、持续和严重程度的风险升高相关,以及与更广泛的身体疾病和自杀导致的早期死亡率增加相关。尽管有效性试验表明,扩大MDD治疗可以逆转许多这些不良反应,但只有少数MDD患者接受治疗,并且大多数治疗者的治疗质量低得令人无法接受。
Data are reviewed on the societal costs of major depressive disorder (MDD). Early-onset MDD is found to predict difficulties in subsequent role transitions, including low educational attainment, high risk of teen child-bearing, marital disruption, and unstable employment. Among people with specific social and productive roles, MDD is found to predict significant decrements in role functioning (e.g., low marital quality, low work performance, low earnings). MDD is also associated with elevated risk of onset, persistence, and severity of a wide range of chronic physical disorders as well as with increased early mortality due to an even wider range of physical disorders and to suicide. Although effectiveness trials show that expanded MDD treatment can reverse many of these adverse effects, only a minority of people with MDD receives treatment and the quality of treatment is unacceptably low among the majority of those in treatment.
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