Effects of interferon alpha on performance in man: a preliminary report
Effects of interferon alpha on performance in man: a preliminary report
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干扰素 α 对人类表现的影响：初步报告
DOI：
10.1007/bf00216072
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发表时间：
2004
影响因子：
3.4
通讯作者：
P. Higgins
中科院分区：
文献类型：
--
作者：
Andrew P. Smith;D. Tyrrell;K. Coyle;P. Higgins
研究了三种剂量的干扰素α（1.5 Mu，0.5 Mu和0.1 Mu）对生产性能的影响。注射1.5 Mu IFN产生的症状和表现变化与流感志愿者中发现的症状和表现变化非常相似。具体来说，志愿者在不确定目标刺激何时出现时反应较慢，但在追踪任务或句法推理任务中没有受损。结果表明，干扰素诱导的中枢神经系统功能的变化提供了一个合理的解释流感对性能的选择性影响。
The effects of three doses of interferon alpha (1.5 Mu, 0.5 Mu and 0.1 Mu) on performance were studied. The injection of 1.5 Mu IFN produced symptoms and performance changes which closely resembled those found in volunteers with influenza. Specifically, volunteers were slower at responding when they were uncertain when a target stimulus would appear, but were not impaired on a pursuit tracking task or syntactic reasoning task. The results suggest that interferon-induced changes in CNS function provide a plausible explanation for the selective effects of influenza on performance.
影响因子：
6.4
作者：
DESTEFANO, E;FRIEDMAN, RM;VILCEK, J
通讯作者：
VILCEK, J