Dissociable cost and benefit encoding of future rewards by mesolimbic dopamine.
Dissociable cost and benefit encoding of future rewards by mesolimbic dopamine.
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中断多巴胺对未来奖励编码的可取消成本和利益编码。
DOI:
10.1038/nn.2460
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发表时间:
2010-01
影响因子:
25
通讯作者:
Phillips PE
中科院分区:
文献类型:
--
作者:
Gan JO;Walton ME;Phillips PE
Reward-predicting cues evoke activity in midbrain dopamine neurons that encodes fundamental attributes of economic value including reward magnitude, delay and uncertainty. Here, we demonstrate that dopamine release in rat nucleus accumbens encodes anticipated benefits but not effort-based response costs unless they are atypically low. This neural separation of costs and benefits indicates that mesolimbic dopamine scales with the value of pending rewards but does not encode the net utility of the action to obtain them.
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通讯作者:
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