Normal values for myocardial deformation within the right heart measured by feature-tracking cardiovascular magnetic resonance imaging.

Normal values for myocardial deformation within the right heart measured by feature-tracking cardiovascular magnetic resonance imaging.
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DOI:
10.1016/j.ijcard.2017.10.106
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发表时间:
2018-02-01
影响因子:
3.5
通讯作者:
Steeds RP
Steeds RP
中科院分区:
医学2区
文献类型:
--
作者:
Liu B;Dardeer AM;Moody WE;Edwards NC;Hudsmith LE;Steeds RP

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右心功能的可重复性和可重复性评估对于监测先天性和获得性心脏病至关重要。越来越多的证据表明,心肌变形(应变和应变率)在确定预后方面具有附加价值。本研究旨在确定使用心血管磁共振特征跟踪(FT-CMR)的右心变形分析的可重复性;并在成人人群中建立正常范围。一个由100名健康受试者组成的队列,包括10名男性和10名女性,年龄在20至70岁之间,每10年一次,无已知的先天性或获得性心血管疾病、高血压、糖尿病、血脂异常或肾脏、肝脏、血液学和全身炎症性疾病,接受了右心室(RV)和右心房(RA)心肌应变和应变率的FT-CMR评估。右心室纵向应变(Ell)为− 21.9 ± 3.24%(FW + S Ell)和− 24.2 ± 3.59%(FW-Ell)。收缩期峰值应变率(S′)为− 1.45 ± 0.39 s− 1(FW + S)和− 1.54 ± 0.41 s− 1(FW)。舒张早期应变率(E′)为1.04 ± 0.26 s-1(FW + S)和1.04 ± 0.33 s-1(FW)。舒张晚期应变率(A′)为0.94 ± 0.33 s− 1(FW + S)和1.08 ± 0.33 s− 1(FW)。RA峰值应变为− 21.1 ± 3.76%。RV Ell(FW + S)的观察者内和观察者间ICC分别为0.92和0.80,而RA峰值应变分别为0.92和0.89。提供了使用FT-CMR的健康个体的RV和RA变形的正常值,具有良好的RV Ell和RA峰值应变再现性。应变率具有次优的再现性,可能无法满足临床使用。
Reproducible and repeatable assessment of right heart function is vital for monitoring congenital and acquired heart disease. There is increasing evidence for the additional value of myocardial deformation (strain and strain rate) in determining prognosis. This study aims to determine the reproducibility of deformation analyses in the right heart using cardiovascular magnetic resonance feature tracking (FT-CMR); and to establish normal ranges within an adult population. A cohort of 100 healthy subjects containing 10 males and 10 females from each decade of life between the ages of 20 and 70 without known congenital or acquired cardiovascular disease, hypertension, diabetes, dyslipidaemia or renal, hepatic, haematologic and systemic inflammatory disorders underwent FT-CMR assessment of right ventricular (RV) and right atrial (RA) myocardial strain and strain rate. RV longitudinal strain (Ell) was − 21.9 ± 3.24% (FW + S Ell) and − 24.2 ± 3.59% (FW-Ell). Peak systolic strain rate (S′) was − 1.45 ± 0.39 s− 1 (FW + S) and − 1.54 ± 0.41 s− 1 (FW). Early diastolic strain rate (E′) was 1.04 ± 0.26 s− 1 (FW + S) and 1.04 ± 0.33 s− 1 (FW). Late diastolic strain rate (A′) was 0.94 ± 0.33 s− 1 (FW + S) and 1.08 ± 0.33 s− 1 (FW). RA peak strain was − 21.1 ± 3.76%. The intra- and inter-observer ICC for RV Ell (FW + S) was 0.92 and 0.80 respectively, while for RA peak strain was 0.92 and 0.89 respectively. Normal values of RV & RA deformation for healthy individuals using FT-CMR are provided with good RV Ell and RA peak strain reproducibility. Strain rate suffered from sub-optimal reproducibility and may not be satisfactory for clinical use.
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发表时间: 2015-03-01
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DOI: 10.1186/1532-429x-14-43
发表时间: 2012-06-21
期刊: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
影响因子: --
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DOI: 10.1093/ejechocard/jen313
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