Resolving human object recognition in space and time.

Resolving human object recognition in space and time.
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DOI:
10.1038/nn.3635
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发表时间:
2014-03
影响因子:
25
通讯作者:
Oliva, Aude
Oliva, Aude
中科院分区:
医学1区
文献类型:
--
作者:
Cichy, Radoslaw Martin;Pantazis, Dimitrios;Oliva, Aude

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要全面了解人脑对物体的处理过程,需要结合大脑活动的空间和时间信息。在这里,我们获得了人类脑磁图(MEG)和功能磁共振成像(fMRI)对92个物体图像的反应。MEG的多变量模式分类揭示了对象处理的时间过程:个体图像被视觉表征识别较早,纵坐标和上级类别水平出现较晚。利用表征相似性分析,我们将人类功能磁共振成像和脑磁图结合起来,以显示早期脑磁图反应与初级视觉皮层(V1)以及后期脑磁图反应与下颞叶皮层(IT)之间的内容特异性对应关系。我们在对象处理过程中发现了短暂的和持续的神经活动,其来源是V1和IT。最后,人类MEG信号与猴子IT的单单元反应相关联。总之,我们的研究结果提供了一个综合的空间和时间分辨视图,在最初几百毫秒的视觉中,人类物体分类。
A comprehensive picture of object processing in the human brain requires combining both spatial and temporal information about brain activity. Here, we acquired human magnetoencephalography (MEG) and functional magnetic resonance imaging (fMRI) responses to 92 object images. Multivariate pattern classification applied to MEG revealed the time course of object processing: whereas individual images were discriminated by visual representations early, ordinate and superordinate category levels emerged relatively later. Using representational similarity analysis, we combine human fMRI and MEG to show content-specific correspondence between early MEG responses and primary visual cortex (V1), and later MEG responses and inferior temporal (IT) cortex. We identified transient and persistent neural activities during object processing, with sources in V1 and IT., Finally, human MEG signals were correlated to single-unit responses in monkey IT. Together, our findings provide an integrated space- and time-resolved view of human object categorization during the first few hundred milliseconds of vision.
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