ConTra v3: a tool to identify transcription factor binding sites across species, update 2017.
ConTra v3: a tool to identify transcription factor binding sites across species, update 2017.
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Contra V3:一种识别物种跨物种的转录因子结合位点的工具,更新2017。
DOI:
10.1093/nar/gkx376
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发表时间:
2017-07-03
影响因子:
14.9
通讯作者:
De Bleser P
中科院分区:
文献类型:
--
作者:
Kreft L;Soete A;Hulpiau P;Botzki A;Saeys Y;De Bleser P
Transcription factors are important gene regulators with distinctive roles in development, cell signaling and cell cycling, and they have been associated with many diseases. The ConTra v3 web server allows easy visualization and exploration of predicted transcription factor binding sites (TFBSs) in any genomic region surrounding coding or non-coding genes. In this updated version, with a completely re-implemented user interface using latest web technologies, users can choose from nine reference organisms ranging from human to yeast. ConTra v3 can analyze promoter regions, 5΄-UTRs, 3΄-UTRs and introns or any other genomic region of interest. Thousands of position weight matrices are available to choose from for detecting specific binding sites. Besides this visualization option, additional new exploration functionality is added to the tool that will automatically detect TFBSs having at the same time the highest regulatory potential, the highest conservation scores of the genomic regions covered by the predicted TFBSs and strongest co-localizations with genomic regions exhibiting regulatory activity. The ConTra v3 web server is freely available at http://bioit2.irc.ugent.be/contra/v3.
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影响因子:
64.5
作者:
Slattery M;Riley T;Liu P;Abe N;Gomez-Alcala P;Dror I;Zhou T;Rohs R;Honig B;Bussemaker HJ;Mann RS
通讯作者:
Mann RS
DOI:
10.1093/bioinformatics/btr064
发表时间:
2011-04-01
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
作者:
Grant CE;Bailey TL;Noble WS
通讯作者:
Noble WS
影响因子:
3
作者:
Heskes T;Eisinga R;Breitling R
通讯作者:
Breitling R
影响因子:
14.9
作者:
Fang F;Blanchette M
通讯作者:
Blanchette M
影响因子:
14.9
作者:
Griffon A;Barbier Q;Dalino J;van Helden J;Spicuglia S;Ballester B
通讯作者:
Ballester B