The Relationship of Motivation and Neurocognition with Functionality in Schizophrenia: A Meta-analytic Review
The Relationship of Motivation and Neurocognition with Functionality in Schizophrenia: A Meta-analytic Review
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精神分裂症动机和神经认知与功能的关系：荟萃分析综述
DOI：
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发表时间：
2018
影响因子：
2.7
通讯作者：
Tania B. Huedo
中科院分区：
文献类型：
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作者：
Antonia Najas;J. Gómez;Tania B. Huedo
神经认知在精神分裂症患者的功能中所起的作用已经得到了广泛的研究，尽管近年来越来越多的关注转向了动机的影响。本研究回顾了精神分裂症患者神经认知和动机与功能之间的关系，考虑了客观/主观功能评估、人口统计学变量以及提及动机时使用的不同术语。对电子数据库的搜索确定了34项符合纳入标准的研究。提取动机与功能、神经认知与功能之间的相关系数。为了更好地理解，还提取了潜在的调节变量。荟萃分析显示，动机和神经认知评估都与功能密切相关，动机和功能结果之间的相关性更强。然而，超过四分之三的结果差异仍然无法解释所检查的调节因素。文章最后对临床实践和未来研究提出了建议。
The role that neurocognition plays in functionality in schizophrenia has been widely examined, although in recent years increasing attention has been paid to the influence of motivation instead. This study provides a review of the relationship of neurocognition and motivation with functionality in schizophrenia, taking into account objective/subjective functionality assessment, demographic variables, and the different terms used when referring to motivation. A search of electronic databases identified 34 studies that met the inclusion criteria for review. Correlation coefficients between motivation and functionality and between neurocognition and functionality were extracted. For a better understanding, potential moderator variables were also extracted. Meta-analysis showed that both motivation and neurocognition assessments were strongly associated with functioning, with correlations between motivation and functional outcomes being stronger. However, more than three-quarters of the variance in outcome remained unexplained by the moderating factors examined. The paper concludes with recommendations for clinical practice and future research.
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