Decreased Fetal Movements: A Sign of Placental SARS-CoV-2 Infection with Perinatal Brain Injury.
Decreased Fetal Movements: A Sign of Placental SARS-CoV-2 Infection with Perinatal Brain Injury.
复制标题
胎儿运动减少:胎盘脑损伤感染胎盘SARS-COV-2的迹象。
DOI:
10.3390/v13122517
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发表时间:
2021-12-15
期刊:
影响因子:
--
通讯作者:
Giannoni E
中科院分区:
文献类型:
--
作者:
Favre G;Mazzetti S;Gengler C;Bertelli C;Schneider J;Laubscher B;Capoccia R;Pakniyat F;Ben Jazia I;Eggel-Hort B;de Leval L;Pomar L;Greub G;Baud D;Giannoni E
Neonatal COVID-19 is rare and mainly results from postnatal transmission. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), however, can infect the placenta and compromise its function. We present two cases of decreased fetal movements and abnormal fetal heart rhythm 5 days after mild maternal COVID-19, requiring emergency caesarean section at 29 + 3 and 32 + 1 weeks of gestation, and leading to brain injury. Placental examination revealed extensive and multifocal chronic intervillositis, with intense cytoplasmic positivity for SARS-CoV-2 spike antibody and SARS-CoV-2 detection by RT-qPCR. Vertical transmission was confirmed in one case, and both neonates developed extensive cystic peri-ventricular leukomalacia.
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DOI:
10.1093/jpids/piaa165
发表时间:
2021-05-01
影响因子:
3.2
作者:
Hopwood, Andrew J.;Jordan-Villegas, Alejandro;Laham, Federico R.
通讯作者:
Laham, Federico R.