Complementary and Alternative Medicine in the Treatment of Rheumatoid Arthritis

Complementary and Alternative Medicine in the Treatment of Rheumatoid Arthritis
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治疗类风湿关节炎的补充和替代医学

DOI:
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发表时间:
2012
期刊:
影响因子:
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通讯作者:
Chenchen Wang
Chenchen Wang
中科院分区:
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文献类型:
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作者:
Chenchen Wang

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类风湿性关节炎是一种系统性、多样性和动态性疾病,其治疗在过去几十年中取得了重大进展。早期使用缓解疾病的抗风湿药物和生物制剂进行积极治疗对于控制炎症活动和预防许多患者的残疾非常有益。然而,最有效的新药价格昂贵,许多类风湿性关节炎患者仍然存在明显的疼痛、活动受限、肌肉力量下降和耐力低下。此外,人们越来越认识到共病在类风湿性关节炎的结局中起着关键作用。例如,心血管并发症是类风湿性关节炎死亡的主要原因,约占所有死亡的一半。导致骨折的骨质疏松症也是类风湿性关节炎发病的主要来源。补充和替代医学治疗以及生活方式行为改变可能在预防类风湿性关节炎相关合并症及其并发症方面发挥作用。类风湿性关节炎的特点是滑膜炎症导致关节破坏,导致严重的长期残疾和显着缩短的预期寿命。许多类风湿性关节炎患者会经历严重的疼痛、功能障碍、心理困扰和负面情绪,但这些症状的药物治疗选择有限。鉴于类风湿性关节炎治疗设备的复杂性,非药物疗法对慢性风湿性疼痛患者越来越有吸引力。最近,关节炎的补充和替代医学疗法得到了大力宣传,并且越来越多的慢性疼痛患者报告正在使用替代疗法。与此同时,临床试验和观察性研究提供了令人鼓舞的证据,表明针灸、身心疗法、中草药和藏药对类风湿性关节炎患者有一定的益处。事实上,综合方法结合了传统医学的精华以及补充和替代医学的智慧。因此,本章综合了目前关于几种补充和替代医学对类风湿关节炎患者疼痛和症状缓解的治疗益处的知识体系,以更好地为我们的患者提供临床决策信息。
Treatment of rheumatoid arthritis, a systemic, diverse and dynamic disorder, has made major progress over the past few decades. Early active treatment with disease-modifying anti-rheumatic drugs and biological agents can be highly beneficial for controlling inflammatory activity and preventing disability in many patients. However, the most effective new drugs are expensive and many patients with rheumatoid arthritis continue to have significant pain, restricted mobility, reduced muscle strength and low endurance. In addition, it is increasingly recognized that co-morbid conditions play a pivotal role in rheumatoid arthritis outcomes. For example, cardiovascular complications are the leading contributor to mortality in rheumatoid arthritis, accounting for approximately one half of all deaths. Osteoporosis, resulting in bone fractures, also represents a major source of morbidity in rheumatoid arthritis. Complementary and alternative medicine treatment and lifestyle behavioral modification may play a role in preventing rheumatoid arthritisassociated comorbidities and their complications. Rheumatoid arthritis is characterized by synovial inflammation that leads to joint destruction, resulting in substantial long-term disability and a significantly shorter life expectancy. Many patients with rheumatoid arthritis experience high levels of pain, functional impairment, psychological distress and negative emotions, but these symptoms have limited pharmacological therapeutic options. Given the complexity of the therapeutic armamentarium used in rheumatoid arthritis, non-pharmacological therapies are increasingly attractive to those with chronic rheumatic pain conditions. Recently, complementary and alternative medicine therapies for arthritis have been heavily advertised and increasing numbers of chronic pain patients report utilizing alternative therapies. At the same time, clinical trials and observational studies have provided encouraging evidence that Acupuncture, Mind-body Therapy, Chinese herbs and Tibetan Medicine have some benefits for patients with rheumatoid arthritis. Indeed, integrative approaches combine the best of conventional medicine and the wisdom of complementary and alternative medicine. Thus, this chapter synthesizes the current body of knowledge on the therapeutic benefits of several types of Complementary and Alternative Medicine on pain and symptom relief in patients with rheumatoid arthritis to better inform clinical decision-making for our patients.
DOI: 10.1089/acm.2008.sar-3
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影响因子: 2.6
作者:
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DOI: 10.1111/j.1751-7141.2008.07565.x
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