Tai chi exercise in patients with chronic heart failure: a randomized clinical trial.

Tai chi exercise in patients with chronic heart failure: a randomized clinical trial.
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DOI:
10.1001/archinternmed.2011.150
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发表时间:
2011-04-25
影响因子:
--
通讯作者:
Phillips, Russell S.
Phillips, Russell S.
中科院分区:
其他
文献类型:
--
作者:
Yeh, Gloria Y.;McCarthy, Ellen P.;Wayne, Peter M.;Stevenson, Lynne W.;Wood, Malissa J.;Forman, Daniel;Davis, Roger B.;Phillips, Russell S.

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初步证据表明,冥想运动可能对慢性收缩期心力衰竭(HF)患者有益;这还没有经过大规模临床样本的严格测试。我们试图研究太极作为标准治疗的辅助手段是否能改善心衰患者的功能能力和生活质量。一项单盲、多地点、平行组、随机对照试验评估了2005年5月1日至2008年9月30日招募的100例收缩期心衰(纽约心脏协会I-III级,左心室射血分数≤40%)门诊患者。进行了以小组为基础的为期12周的太极锻炼计划(n=50)或时间匹配的教育(n=50,对照组)。结果测量包括运动能力(6分钟步行测试和峰值摄氧量)和疾病特异性生活质量(明尼苏达州心力衰竭患者问卷)。患者平均(SD)年龄为67(11)岁;基线值为左心室射血分数29%(8%)和峰值摄氧量13.5 mL/kg/min;纽约心脏协会心衰分级中位数为II级。在研究结束时,与太极拳组和对照组相比,6分钟步行距离和峰值摄氧量的变化没有显著差异(中位数变化[第一四分位数,第三四分位数],35 [- 2,51]vs 2[- 7, 54]米,P= 0.95;和1.1 [- 1.1,1.5]vs - 0.5 [- 1.2, 1.8] mL/kg/min, P= 0.81);然而,太极拳组患者的生活质量有更大的改善(明尼苏达州心力衰竭患者问卷,- 19 [- 23,- 3]vs . 1 [- 16, 3], P=.02)。太极也改善了运动自我效能(心脏运动自我效能量表,0.1 [0.1,0.6]vs - 0.3 [- 0.5, 0.2], P< 0.001)和情绪(情绪状态概况,- 6 [- 17,1]vs - 1 [- 13,10], P= 0.01)。太极拳运动可改善心衰患者的生活质量、情绪和运动自我效能感。clinicaltrials.gov识别码:NCT00110227
Preliminary evidence suggests that meditative exercise may have benefits for patients with chronic systolic heart failure (HF); this has not been rigorously tested in a large clinical sample. We sought to investigate whether tai chi, as an adjunct to standard care, improves functional capacity and quality of life in patients with HF. A single-blind, multisite, parallel-group, randomized controlled trial evaluated 100 outpatients with systolic HF (New York Heart Association class I-III, left ventricular ejection fraction ≤40%) who were recruited between May 1, 2005, and September 30, 2008. A group-based 12-week tai chi exercise program (n=50) or time-matched education (n=50, control group) was conducted. Outcome measures included exercise capacity (6-minute walk test and peak oxygen uptake) and disease-specific quality of life (Minnesota Living With Heart Failure Questionnaire). Mean (SD) age of patients was 67(11) years; baseline values were left ventricular ejection fraction, 29% (8%) and peak oxygen uptake, 13.5 mL/kg/min; the median New York Heart Association class of HF was class II. At completion of the study, there were no significant differences in change in 6-minute walk distance and peak oxygen uptake (median change [first quartile, third quartile], 35 [−2, 51] vs 2 [−7, 54] meters, P=.95; and 1.1 [−1.1, 1.5] vs −0.5 [−1.2, 1.8] mL/kg/min, P=.81) when comparing tai chi and control groups; however, patients in the tai chi group had greater improvements in quality of life (Minnesota Living With Heart Failure Questionnaire, −19 [−23, −3] vs 1 [−16, 3], P=.02). Improvements with tai chi were also seen in exercise self-efficacy (Cardiac Exercise Self-efficacy Instrument, 0.1 [0.1, 0.6] vs −0.3 [−0.5, 0.2], P<.001) and mood (Profile of Mood States total mood disturbance, −6 [−17, 1] vs −1 [−13, 10], P=.01). Tai chi exercise may improve quality of life, mood, and exercise self-efficacy in patients with HF. clinicaltrials.gov Identifier: NCT00110227
DOI: 10.1249/00005768-198205000-00012
发表时间: 1982-01-01
期刊: MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
影响因子: --
作者:
BORG, GAV
通讯作者: BORG, GAV
DOI: 10.1161/01.cir.99.9.1173
发表时间: 1999-03-09
期刊: CIRCULATION
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发表时间: 1999-11-01
影响因子: --
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发表时间: 2002-06-13
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