Innervation zones of fasciculating motor units: observations by a linear electrode array.

Innervation zones of fasciculating motor units: observations by a linear electrode array.
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引人入胜的电动机单元的神经区域:通过线性电极阵列进行观察。

DOI:
10.3389/fnhum.2015.00239
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发表时间:
2015
影响因子:
2.9
通讯作者:
Zhou P
Zhou P
中科院分区:
医学3区
文献类型:
--
作者:
Jahanmiri-Nezhad F;Barkhaus PE;Rymer WZ;Zhou P

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本研究使用20通道线性肌电图(EMG)电极阵列检测了健康受试者和肌萎缩侧索硬化症(ALS)患者肱二头肌的神经支配区(IZ)。光栅图的个别波形电位进行了研究,以估计运动单位IZ。虽然这项工作主要集中在肌束震颤电位(FP),有限数量的运动单位电位(MUP)自愿活动的12名健康和7名ALS受试者也进行了检查。与健康和ALS受试者中自愿激活的MUP相比,在成束单位中观察到MUP和分散的IZs的异常传播。这些发现可能与ALS运动神经元变性后的肌纤维再支配以及FP与自愿MUP相比的不同起源部位有关。
This study examines the innervation zone (IZ) in the biceps brachii muscle in healthy subjects and those with amyotrophic lateral sclerosis (ALS) using a 20-channel linear electromyogram (EMG) electrode array. Raster plots of individual waveform potentials were studied to estimate the motor unit IZ. While this work mainly focused on fasciculation potentials (FPs), a limited number of motor unit potentials (MUPs) from voluntary activity of 12 healthy and seven ALS subjects were also examined. Abnormal propagation of MUPs and scattered IZs were observed in fasciculating units, compared with voluntarily activated MUPs in healthy and ALS subjects. These findings can be related to muscle fiber reinnervation following motor neuron degeneration in ALS and the different origin sites of FPs compared with voluntary MUPs.
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期刊: NEUROLOGY
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