Reduction in muscarinic receptor binding in limbic areas of Alzheimer brain.

Reduction in muscarinic receptor binding in limbic areas of Alzheimer brain.
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阿尔茨海默脑边缘区域毒蕈碱受体结合减少。

DOI:
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发表时间:
1984
影响因子:
11
通讯作者:
U. Rinne
U. Rinne
中科院分区:
医学1区
文献类型:
--
作者:
J. Rinne;J. Rinne;K. Laakso;L. Paljärvi;U. Rinne

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先生:许多研究表明,阿尔茨海默病患者的突触前胆碱能神经元明显丧失。 2 边缘结构出现显着的组织学变化,特别是杏仁核和海马体。34 研究还表明,阿尔茨海默病患者海马体神经元的损失是正常衰老过程中的五倍。最近的研究表明,等树突神经元从Meynert基底核投射到大脑皮层,从Broca斜带和内侧隔核投射到海马
Sir: It has been shown in many studies that there is a marked loss of presynaptic cholinergic neurons in patients with Alzheimer's disease.' 2 Prominent histological changes are seen in the limbic structures, especially the amygdala and hippocampus.34 It has also been shown that the neuronal loss in the hippocampus of patients with Alzheimer's disease is five times greater than in normal ageing.' Recent studies have shown that isodendritic neurons which project from the nucleus basalis of Meynert to the cerebral cortex and from the diagonal band of Broca and the medial septal nucleus to hippocampus
DOI: 10.1001/archneur.1980.00500590049006
发表时间: 1980-01-01
影响因子: --
作者:
HERZOG, AG;KEMPER, TL
通讯作者: KEMPER, TL