Immediate hypersensitivity reactions to penicillin and related antibiotics
Immediate hypersensitivity reactions to penicillin and related antibiotics
复制标题
对青霉素和相关抗生素的立即过敏反应
DOI：
10.1111/j.1365-2222.1988.tb02904.x
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发表时间：
1988
影响因子：
6.1
通讯作者：
N. Adkinson
中科院分区：
文献类型：
--
作者：
M. Weiss;N. Adkinson
Introduction The discovery of penicillin by Fleming led to tremendous benefits in clinical medicine. Penicillin quickly became one of the most commonly prescribed drugs in the world. Despite a wide therapeutic index, it soon became clear that the penicillins could produce a vast array of immunological responses that could cause severe and fatal allergic reactions in some patients. The first reported case of anaphylaxis due to penicillin was in 1946 [I], and the first reported death was in 1949 [2]. Subsequently, a broad spectrum of allergic reactions to penicillin have been recognized. Available data do not permit exact conclusions as to the true frequency of allergic reactions to penicillin but they are reported to occur from 0-7 to S% of treatment courses in different studies [3], Allergenicity of penicillins is the major clinical problem that precludes the use of this class of antibiotics in a significant portion of the general population who are believed to be sensitive. In this article we will discuss allergic reactions to ^-lactam antibiotics, with special emphasis on IgE-dependent reactions in man.
影响因子：
14.2
作者：
SOLLEY, GO;GLEICH, GJ;VANDELLEN, RG
通讯作者：
VANDELLEN, RG
儿童昆虫过敏的流行病学研究。
DOI：
10.1016/s0022-3476(83)80649-0
发表时间：
1983
期刊：
The Journal of pediatrics
影响因子：
--
作者：
Schuberth,KC;Lichtenstein,LM;Kagey-Sobotka,A;Szklo,M;Kwiterovich,KA;Valentine,MD
通讯作者：
Valentine,MD