miR2Disease: a manually curated database for microRNA deregulation in human disease.
miR2Disease: a manually curated database for microRNA deregulation in human disease.
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miR2Disease：人类疾病中 microRNA 失调的手动数据库
DOI：
10.1093/nar/gkn714
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发表时间：
2009-01
影响因子：
14.9
通讯作者：
Liu Y
中科院分区：
文献类型：
--
作者：
Jiang Q;Wang Y;Hao Y;Juan L;Teng M;Zhang X;Li M;Wang G;Liu Y
“miR 2Disease”是一个人工管理的数据库，旨在提供各种人类疾病中microRNA失调的综合资源。目前版本的miR 2Disease通过回顾600多篇已发表的论文，记录了1939年299种人类microRNA与94种人类疾病之间的关系。大约七分之一的microRNA与疾病的关系代表了失调的microRNA在人类疾病中的致病作用。miR 2Disease中的每个条目包含关于microRNA-疾病关系的详细信息，包括microRNA ID、疾病名称、microRNA-疾病关系的简要描述、microRNA的表达模式、microRNA表达的检测方法、实验验证的microRNA靶基因和参考文献。miR 2Disease提供了一个用户友好的界面，可以通过microRNA ID、疾病名称或靶基因方便地检索每个条目。此外，miR 2Disease提供了一个提交页面，允许研究人员提交尚未记录的已建立的microRNA-疾病关系。一旦提交审查委员会批准，提交的记录将被纳入数据库。miR 2Disease可在http://www.miR2Disease.org上免费获得。
‘miR2Disease’, a manually curated database, aims at providing a comprehensive resource of microRNA deregulation in various human diseases. The current version of miR2Disease documents 1939 curated relationships between 299 human microRNAs and 94 human diseases by reviewing more than 600 published papers. Around one-seventh of the microRNA–disease relationships represent the pathogenic roles of deregulated microRNA in human disease. Each entry in the miR2Disease contains detailed information on a microRNA–disease relationship, including a microRNA ID, the disease name, a brief description of the microRNA–disease relationship, an expression pattern of the microRNA, the detection method for microRNA expression, experimentally verified target gene(s) of the microRNA and a literature reference. miR2Disease provides a user-friendly interface for a convenient retrieval of each entry by microRNA ID, disease name, or target gene. In addition, miR2Disease offers a submission page that allows researchers to submit established microRNA–disease relationships that are not documented. Once approved by the submission review committee, the submitted records will be included in the database. miR2Disease is freely available at http://www.miR2Disease.org.
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影响因子：
4.3
作者：
Fraga, MF;Esteller, M
通讯作者：
Esteller, M
影响因子：
14.9
作者：
Griffiths-Jones, S
通讯作者：
Griffiths-Jones, S
影响因子：
7.3
作者：
Lehmann, U.;Hasemeier, B.;Kreipe, H.
通讯作者：
Kreipe, H.
影响因子：
64.5
作者：
Lewis, BP;Shih, IH;Burge, CB
通讯作者：
Burge, CB
影响因子：
14.9
作者：
Betel D;Wilson M;Gabow A;Marks DS;Sander C
通讯作者：
Sander C