Order from the Order: How a Spatiotemporal Genetic Program Is Encoded in a 2-D Genetic Map of the Bacterial Chromosome
Order from the Order: How a Spatiotemporal Genetic Program Is Encoded in a 2-D Genetic Map of the Bacterial Chromosome
复制标题
来自秩序的秩序:时空遗传程序如何编码在细菌染色体的二维遗传图中
DOI:
10.1159/000368852
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发表时间:
2015
影响因子:
1.2
通讯作者:
A. Travers
中科院分区:
文献类型:
--
作者:
G. Muskhelishvili;A. Travers
In this article, we sketch out a holistic methodology used for exploring how the genetic program is encoded in a 2-D genetic map of a bacterial chromosome. We argue that the major problem resides in the conceptual integration of the two logically distinct types of information encoded in the chiral double-helical DNA polymer. This integration is accomplished by mapping the genetic function on the genomic sequence organisation and therefore is potentially applicable to any chromosome. The vast generalisation achieved by this approach necessarily ignores exquisite details, yet it is fundamental in providing comprehensive methodology for exploring the role of the DNA sequence organisation in harnessing genetic information and sustaining biological order.
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影响因子:
15.9
作者:
Tse-Dinh,YC;Qi,H;Menzel,R
通讯作者:
Menzel,R
影响因子:
--
作者:
Patrick Sobetzko;M. Glinkowska;A. Travers;G. Muskhelishvili
通讯作者:
Patrick Sobetzko;M. Glinkowska;A. Travers;G. Muskhelishvili
影响因子:
5.6
作者:
DREW, HR;TRAVERS, AA
通讯作者:
TRAVERS, AA
影响因子:
11.4
作者:
ZECHIEDRICH, EL;OSHEROFF, N
通讯作者:
OSHEROFF, N
影响因子:
6.4
作者:
Jiang X;Sobetzko P;Nasser W;Reverchon S;Muskhelishvili G
通讯作者:
Muskhelishvili G