Stress Distribution in a Bilayer Elastic Model of a Coronary Artery

Stress Distribution in a Bilayer Elastic Model of a Coronary Artery
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冠状动脉双层弹性模型中的应力分布

DOI:
10.1115/1.4007863
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发表时间:
2013
期刊:
J Applied Mechanics
影响因子:
--
通讯作者:
Nakayama Y
Nakayama Y
中科院分区:
--
文献类型:
--
作者:
Takamizawa K;Nakayama Y

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在早期对动脉应力分布的研究中,经常使用单层壁模型。动脉壁由三层组成:内膜、中膜和外膜。尽管内膜作为血液和动脉壁之间的界面很重要,但作为年轻健康血管中抵抗血压的应力支撑层,在机械上可以忽略不计。中膜和外膜层被认为可以支持血压。最近,在分离的中膜和外膜中研究了猪冠状动脉的残余应变和本构规律。本研究利用通过这些研究获得的数据,进行了考虑各层残余应力(应变)的应力分析,并计算了双层模型的残余应变和应力。周向残余应力在内部区域为压应力,在外部区域为拉应力,并且在中膜和外膜之间的边界处具有不连续性。生理条件下,中膜周向应力峰值出现在中膜与外膜交界处,外膜内几乎呈平坦分布。这种模式在高血压情况下不会改变。这些结果表明,媒体中发生了高血压的重塑。
In earlier studies on stress distribution in arteries, a monolayer wall model was often used. An arterial wall consists of three layers, the intima, the media, and the adventitia. The intima is mechanically negligible as a stress supporting layer against the blood pressure in young healthy vessels, although it is important as an interface between blood and arterial wall. The media and adventitia layers are considered to support blood pressure. Recently, residual strain and a constitutive law for porcine coronary arteries have been investigated in separated media and adventitia. Using the data obtained through these investigations, a stress analysis considering residual stress (strain) in each layer was performed in this study, and residual strain and stress were computed for a bilayer model. The circumferential residual stress was compressive in the inner region, tensile in the outer region, and had discontinuity at the boundary between the media and adventitia. A peak circumferential stress occurred in the media at the boundary between the media and adventitia under a physiological condition, and an almost flat distribution was obtained in the adventitia. This pattern does not change under a hypertensive condition. These results suggest that a remodeling with hypertension occurs in the media.
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