The evolution of the GALactose utilization pathway in budding yeasts.
The evolution of the GALactose utilization pathway in budding yeasts.
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DOI:
10.1016/j.tig.2021.08.013
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发表时间:
2022-01
期刊:
影响因子:
--
通讯作者:
Rokas A
中科院分区:
文献类型:
--
作者:
Harrison MC;LaBella AL;Hittinger CT;Rokas A
The Leloir galactose utilization or GAL pathway of budding yeasts, including that of the baker’s yeast Saccharomyces cerevisiae and the opportunistic human pathogen Candida albicans, breaks down the sugar galactose for energy and biomass production. The GAL pathway has long served as a model system for understanding how eukaryotic metabolic pathways, including their modes of regulation, evolve. More recently, the physical linkage of the structural genes GAL1, GAL7, and GAL10 in diverse budding yeast genomes has been used as a model for understanding the evolution of gene clustering. In this review, we summarize exciting recent work on three different aspects of this iconic pathway’s evolution: gene cluster organization, GAL gene regulation, and the population genetics of the GAL pathway.
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影响因子:
12.3
作者:
Jones S
通讯作者:
Jones S
DOI:
10.1016/j.cub.2021.01.074
发表时间:
2021-04-26
期刊:
Current biology : CB
影响因子:
--
作者:
Li Y;Steenwyk JL;Chang Y;Wang Y;James TY;Stajich JE;Spatafora JW;Groenewald M;Dunn CW;Hittinger CT;Shen XX;Rokas A
通讯作者:
Rokas A
影响因子:
3.3
作者:
Caudy AA;Guan Y;Jia Y;Hansen C;DeSevo C;Hayes AP;Agee J;Alvarez-Dominguez JR;Arellano H;Barrett D;Bauerle C;Bisaria N;Bradley PH;Breunig JS;Bush E;Cappel D;Capra E;Chen W;Clore J;Combs PA;Doucette C;Demuren O;Fellowes P;Freeman S;Frenkel E;Gadala-Maria D;Gawande R;Glass D;Grossberg S;Gupta A;Hammonds-Odie L;Hoisos A;Hsi J;Hsu YH;Inukai S;Karczewski KJ;Ke X;Kojima M;Leachman S;Lieber D;Liebowitz A;Liu J;Liu Y;Martin T;Mena J;Mendoza R;Myhrvold C;Millian C;Pfau S;Raj S;Rich M;Rokicki J;Rounds W;Salazar M;Salesi M;Sharma R;Silverman S;Singer C;Sinha S;Staller M;Stern P;Tang H;Weeks S;Weidmann M;Wolf A;Young C;Yuan J;Crutchfield C;McClean M;Murphy CT;Llinás M;Botstein D;Troyanskaya OG;Dunham MJ
通讯作者:
Dunham MJ
影响因子:
3.6
作者:
ACOSTA, PB;GROSS, KC
通讯作者:
GROSS, KC
DOI:
10.1073/pnas.0404319101
发表时间:
2004-09-28
影响因子:
11.1
作者:
Hittinger, CT;Rokas, A;Carroll, SB
通讯作者:
Carroll, SB