Quantitative analysis of unruptured intracranial aneurysm wall thickness and enhancement using 7T high resolution, black blood magnetic resonance imaging.
Quantitative analysis of unruptured intracranial aneurysm wall thickness and enhancement using 7T high resolution, black blood magnetic resonance imaging.
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使用7T高分辨率黑血磁共振成像定量分析未破裂颅内动脉瘤壁厚度和增强情况
DOI：
10.1136/neurintsurg-2021-017688
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发表时间：
2022-07
影响因子：
4.8
通讯作者：
中科院分区：
文献类型：
--
作者：
本研究旨在使用 7T MRI 量化颅内动脉瘤壁厚度 (AWT) 和增强情况，及其与动脉瘤大小和类型的关系。纳入 27 名患有 29 个颅内动脉瘤的患者。使用具有 0.4 mm 各向同性分辨率的三维 T1 加权前后对比快速自旋回波。 AWT 定义为预对比图像上动脉瘤壁信号强度分布的半峰全宽。增强比（ER）定义为动脉瘤壁的信号强度相对于脑实质的信号强度。研究了 AWT、ER 和动脉瘤大小和类型之间的关系。 7T MRI 显示 AWT 存在较大变化（范围 0.11–1.24 mm）。大动脉瘤（>7 mm）的壁比小动脉瘤（≤7 mm）厚（0.49±0.05 vs 0.41±0.05 mm，p<0.001）。囊状动脉瘤和梭状动脉瘤的 AWT 相似 (p=0.546)。在每个动脉瘤内，29 个动脉瘤中的 28 个动脉瘤中，较厚的动脉瘤壁与增强增强相关（平均 r=0.65，p<0.05）。在增强节段（ER > 1）中观察到比非增强节段更厚的壁（0.53±0.09 vs 0.38±0.07 mm，p<0.001）。 7T 的图像质量得到改善，可以量化颅内 AWT 和增强。在较大的动脉瘤中观察到较厚的动脉瘤壁，并且与更强的增强相关。
This study was performed to quantify intracranial aneurysm wall thickness (AWT) and enhancement using 7T MRI, and their relationship with aneurysm size and type. 27 patients with 29 intracranial aneurysms were included. Three-dimensional T1 weighted pre- and post-contrast fast spin echo with 0.4 mm isotropic resolution was used. AWT was defined as the full width at half maximum on profiles of signal intensity across the aneurysm wall on pre-contrast images. Enhancement ratio (ER) was defined as the signal intensity of the aneurysm wall over that of the brain parenchyma. The relationships between AWT, ER, and aneurysm size and type were investigated. 7T MRI revealed large variations in AWT (range 0.11–1.24 mm). Large aneurysms (>7 mm) had thicker walls than small aneurysms (≤7 mm) (0.49±0.05 vs 0.41±0.05 mm, p<0.001). AWT was similar between saccular and fusiform aneurysms (p=0.546). Within each aneurysm, a thicker aneurysm wall was associated with increased enhancement in 28 of 29 aneurysms (average r=0.65, p<0.05). Thicker walls were observed in enhanced segments (ER >1) than in non-enhanced segments (0.53±0.09 vs 0.38±0.07 mm, p<0.001). Improved image quality at 7T allowed quantification of intracranial AWT and enhancement. A thicker aneurysm wall was observed in larger aneurysms and was associated with stronger enhancement.
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影响因子：
37.8
作者：
Go AS;Mozaffarian D;Roger VL;Benjamin EJ;Berry JD;Blaha MJ;Dai S;Ford ES;Fox CS;Franco S;Fullerton HJ;Gillespie C;Hailpern SM;Heit JA;Howard VJ;Huffman MD;Judd SE;Kissela BM;Kittner SJ;Lackland DT;Lichtman JH;Lisabeth LD;Mackey RH;Magid DJ;Marcus GM;Marelli A;Matchar DB;McGuire DK;Mohler ER 3rd;Moy CS;Mussolino ME;Neumar RW;Nichol G;Pandey DK;Paynter NP;Reeves MJ;Sorlie PD;Stein J;Towfighi A;Turan TN;Virani SS;Wong ND;Woo D;Turner MB;American Heart Association Statistics Committee and Stroke Statistics Subcommittee
通讯作者：
American Heart Association Statistics Committee and Stroke Statistics Subcommittee
DOI：
10.3174/ajnr.a4734
发表时间：
2016-07
期刊：
AJNR. American journal of neuroradiology
影响因子：
--
作者：
Blankena R;Kleinloog R;Verweij BH;van Ooij P;Ten Haken B;Luijten PR;Rinkel GJ;Zwanenburg JJ
通讯作者：
Zwanenburg JJ
影响因子：
3.5
作者：
Kalsoum, E.;Negrier, A. Chabernaud;Hodel, J.
通讯作者：
Hodel, J.
DOI：
10.1007/978-3-319-04981-6_3
发表时间：
2015-01-01
期刊：
Acta neurochirurgica. Supplement
影响因子：
--
作者：
Sherif, Camillo;Kleinpeter, Gunther;Krssak, Martin
通讯作者：
Krssak, Martin
影响因子：
3.5
作者：
Omodaka, S.;Endo, H.;Tominaga, T.
通讯作者：
Tominaga, T.