What is breast cancer doing before we can detect it?
What is breast cancer doing before we can detect it?
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在我们发现乳腺癌之前，它会发生什么？
DOI：
10.1002/jso.2930300307
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发表时间：
1985
影响因子：
2.5
通讯作者：
J. Spratt
中科院分区：
文献类型：
--
作者：
J. Spratt;J. Spratt
乳腺癌是一种细胞疾病，可检测期的细胞动力学事件具有重要的临床意义。这些事件包括复制速率、伴有远处转移的血管生成、细胞死亡速率以及产生可检测的以及随后有症状的肿瘤团块所需的细胞数量。使用乳腺癌检测和示范项目的数据以及文献中的重要报告报告了对这些事件及其相互关系的考虑。据估计，可预测时期的生长速度比可粗略测量的乳腺癌的生长速度要快得多，这与冈珀兹生长的预测一致。
Breast cancer is a cellular disease and the cellular kinetic events in the predetectable period are of great clinical significance. Such events include rate of replication, angiogenesis with distant metastasis, rate of cell death, and the number of cells needed to produce a detectable and later a symptomatic mass of neoplasm. A consideration of these events and their interrelatedness is reported using data from The Breast Cancer Detection and Demonstration Projects and significant reports in the literature. Growth rates in the predetectable period are estimated to be much faster than those that occur with grossly measurable breast cancers in keeping with the prediction of Gompertzian growth.
影响因子：
11.2
作者：
C. Osborne;C. Osborne;D. Boldt;G. Clark;J. Trent
通讯作者：
C. Osborne;C. Osborne;D. Boldt;G. Clark;J. Trent
半固体培养基中肿瘤集落内细胞数量及其扁球体生长的定量。
影响因子：
11.2
作者：
MeyskensJr,FL;Thomson,SP;Moon,TE
通讯作者：
Moon,TE