Pigment-Dispersing Factor Signaling and Circadian Rhythms in Insect Locomotor Activity.

Pigment-Dispersing Factor Signaling and Circadian Rhythms in Insect Locomotor Activity.
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DOI:
10.1016/j.cois.2014.05.002
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发表时间:
2014-07-01
影响因子:
5.3
通讯作者:
Yao, Zepeng
Yao, Zepeng
中科院分区:
农林科学2区
文献类型:
--
作者:
Shafer, Orie T.;Yao, Zepeng

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Though expressed in relatively few neurons in insect nervous systems, pigment-dispersing factor (PDF) plays many roles in the control of behavior and physiology. PDF’s role in circadian timekeeping is its best-understood function and the focus of this review. Here we recount the isolation and characterization of insect PDFs, review the evidence that PDF acts as a circadian clock output factor, and discuss emerging models of how PDF functions within circadian clock neuron network of Drosophila, the species in which this peptide’s circadian roles are best understood.
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