Combined Effect of Slow Gait Speed and Depressive Symptoms on Incident Disability in Older Adults.
Combined Effect of Slow Gait Speed and Depressive Symptoms on Incident Disability in Older Adults.
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慢步速和抑郁症状对老年人意外残疾的综合影响。
DOI：
10.1016/j.jamda.2015.08.012
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发表时间：
2016
影响因子：
7.6
通讯作者：
Suzuki T
中科院分区：
文献类型：
--
作者：
Tsutsumimoto K;Doi T;Shimada H;Makizako H;Hotta R;Nakakubo S;Suzuki T
目的：阐明步速缓慢和抑郁症状的组合是否导致老年人发生意外残疾的风险高于任何一种症状。设计前瞻性队列研究。背景设在日本爱知县大部市。参与者是4038名符合研究纳入标准的老年人(男性48.7%，平均年龄671岁)。测量收集了基线后33个月[中位数31个月(四分位数范围29-32个月)]的意外残疾数据。我们每月监测事故伤残，定义为日本个人支持或护理的长期护理保险认证。基线测量包括事件残疾、步态速度和用于评估抑郁症状的老年抑郁量表的协变量。研究了步态缓慢、抑郁症状或其共同出现与意外残疾之间的关系。结果在调整后的Cox比例风险回归模型中，对照组参与者是参考对象。步态缓慢和抑郁症状并存的参与者发生残疾的风险更大[风险比(HR)3.08，可信区间(CI)95%2.00-4.75]。单独步速较慢(HR 2.44，CI 95%1.71~3.47)和有抑郁症状(HR 1.60，CI 95%1.01~2.53)的受试者风险较大。
ObjectivesTo elucidate whether a combination of slow gait speed and depressive symptoms result in higher risk of incident disability in older adults than either symptom individually.DesignProspective cohort study.SettingObu City, Aichi Prefecture, Japan.ParticipantsParticipants were 4038 older adults (48.7% male, mean age = 71 years) who met the study inclusion criteria.MeasurementsLongitudinal data on incident disability were collected up to 33 months [median 31 months (interquartile range 29–32 months)] after baseline. We monitored monthly incident disability, defined as Japanese long-term care insurance certification for personal support or care. Baseline measurements included covariates for incident disability, gait speed, and the Geriatric Depression Scale for assessing depressive symptoms. The associations between slow gait, depressive symptoms, or their co-occurrence, and incident disability were examined.ResultsControl participants were the reference in an adjusted Cox proportional hazard regression model. Participants with co-occurring slow gait and depressive symptoms showed a greater risk of incident disability [hazard ratio (HR) 3.08, confidence interval (CI) 95% 2.00–4.75]. Greater risk was also found for participants with slow gait speed alone (HR 2.44, CI 95% 1.71–3.47) and depressive symptoms alone (HR 1.60, CI 95% 1.01–2.53).ConclusionsOlder adults with both risk factors may require early detection and physical and psychological intervention.
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肌肉骨骼疼痛患者步行速度降低的决定因素。
影响因子：
3.9
作者：
S. Ayis;S. Ebrahim;Susan Williams;P. Jüni;P. Dieppe
通讯作者：
P. Dieppe
影响因子：
8.3
作者：
Kapfhammer HP
通讯作者：
Kapfhammer HP
DOI：
10.1093/geronb/59.4.s238
发表时间：
2004-07
期刊：
The journals of gerontology. Series B, Psychological sciences and social sciences
影响因子：
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作者：
Miles G. Taylor;S. Lynch
通讯作者：
Miles G. Taylor;S. Lynch
DOI：
10.1111/j.1532-5415.2012.04114.x
发表时间：
2012-09-01
影响因子：
6.3
作者：
Sanders, Joost B.;Bremmer, Marijke A.;Beekman, Aartjan T. F.
通讯作者：
Beekman, Aartjan T. F.
影响因子：
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作者：
Ensrud, Kristine E.;Ewing, Susan K.;Cummings, Steven R.
通讯作者：
Cummings, Steven R.