Prolonged hyperinsulinemia after subcutaneous injection of 2400 U regular insulin in a suicide attempt: Time course of serum insulin with frequent measurements.

Prolonged hyperinsulinemia after subcutaneous injection of 2400 U regular insulin in a suicide attempt: Time course of serum insulin with frequent measurements.
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DOI:
10.1111/j.2040-1124.2012.00211.x
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发表时间:
2012-10-18
影响因子:
3.2
通讯作者:
Ikegami H
Ikegami H
中科院分区:
医学3区
文献类型:
--
作者:
Hiromine Y;Kawabata Y;Yamauchi T;Noso S;Babaya N;Harada T;Ito H;Ikegami H

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我们研究了一名在自杀未遂时注射大量常规胰岛素的患者的血清胰岛素水平的时间过程。一名58岁女性通过皮下注射2400 U常规胰岛素企图自杀。 到达时,血清葡萄糖水平为2.4 mmol/L(44 mg/dL),血清胰岛素水平为40,000 pmol/L(5700 μIU/mL)。    血清胰岛素水平较高,注射后13 h达到最大值110,000 pmol/L(16,000 μIU/mL),随后开始快速下降,随后缓慢下降,高胰岛素血症持续时间长达注射后5天。    (J Diabetes Invest,doi:10.1111/j.2040 - 1124.2012.00211.x,2012)
We studied the time course of serum insulin level in a patient who injected large amounts of regular insulin in an attempted suicide. A 58‐year‐old woman attempted suicide by subcutaneously injecting herself with 2400 U regular insulin. On arrival, the serum glucose level was 2.4 mmol/L (44 mg/dL) and the serum insulin level was 40,000 pmol/L (5700 μIU/mL). The serum insulin level was high, with a maximum of 110,000 pmol/L (16,000 μIU/mL) at 13 h after injection, followed by an initial rapid decrease and a subsequent slow decrease, with hyperinsulinemia lasting as long as 5 days after injection. (J Diabetes Invest, doi: 10.1111/j.2040‐1124.2012.00211.x, 2012)
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