Negative Vaccine Attitudes and Intentions to Vaccinate Against Covid-19 in Relation to Smoking Status: A Population Survey of UK Adults
Negative Vaccine Attitudes and Intentions to Vaccinate Against Covid-19 in Relation to Smoking Status: A Population Survey of UK Adults
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与吸烟状况相关的消极疫苗态度和接种 Covid-19 疫苗的意愿：对英国成年人的人口调查
DOI：
10.1101/2020.12.17.20248396
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发表时间：
2020
影响因子：
4.7
通讯作者：
D. Fancourt
中科院分区：
文献类型：
--
作者：
S. Jackson;E. Paul;Jamie Brown;A. Steptoe;D. Fancourt
简介：我们在英国的一个大样本中，根据吸烟状况，研究了对疫苗的一般负面态度以及接种COVID-19疫苗的具体意图的差异。方法：数据来自2020年9月至10月参加Covid-19社会研究的29，148名成年人。线性回归分析研究了吸烟状况（当前/以前/从未）与四种类型的一般消极疫苗态度之间的关联：对疫苗益处的不信任，对不可预见的影响的担忧，对商业暴利的担忧以及对自然免疫的偏好。多项逻辑回归分析了吸烟状况与不确定性和不愿接种新冠疫苗之间的关系。协变量包括社会人口学特征和诊断的健康状况。结果如下：相对于从不吸烟者和曾经吸烟者，目前吸烟者报告对疫苗益处的不信任程度显著更高，更担心不可预见的未来影响，更担心商业暴利，并且对自然免疫有更强的偏好（Badjs 0.16-0.36，p<0.001）。目前的吸烟者更有可能不确定（27.6% vs. 22.7%从不吸烟者：RRadj 1.43 [95%CI 1.31-1.56]; vs. 19.3%既往吸烟者：RRadj 1.55 [1.41-1.73]）或不愿意（21.5% vs. 11.6%从不吸烟者：RRadj 2.12 [1.91-2.34]; vs. 14.7%曾吸烟者：RRadj 1.53 [1.37-1.71]）接种新冠疫苗。结论：与从不吸烟和曾经吸烟的人相比，目前吸烟的人对疫苗总体上持更消极的态度，更有可能犹豫不决或不愿意接种新冠疫苗。由于吸烟者人数不成比例地高，属于社会聚集和弱势社会经济群体，这一群体的疫苗接种率较低也可能加剧健康不平等。
Introduction: We examined differences in negative attitudes towards vaccines in general, and intentions to vaccinate against Covid-19 specifically, by smoking status in a large sample of adults in the UK. Method: Data were from 29,148 adults participating in the Covid-19 Social Study in September-October 2020. Linear regression analyses examined associations between smoking status (current/former/never) and four types of general negative vaccine attitudes: mistrust of vaccine benefit, worries about unforeseen effects, concerns about commercial profiteering, and preference for natural immunity. Multinomial logistic regression examined associations between smoking status and uncertainty and unwillingness to be vaccinated for Covid-19. Covariates included sociodemographic characteristics and diagnosed health conditions. Results: Relative to never and former smokers, current smokers reported significantly greater mistrust of vaccine benefit, were more worried about unforeseen future effects, had greater concerns about commercial profiteering, and had a stronger preference for natural immunity (Badjs 0.16-0.36, p<0.001). Current smokers were more likely to be uncertain (27.6% vs. 22.7% of never smokers: RRadj 1.43 [95%CI 1.31-1.56]; vs. 19.3% of former smokers: RRadj 1.55 [1.41-1.73]) or unwilling (21.5% vs. 11.6% of never smokers: RRadj 2.12 [1.91-2.34]; vs. 14.7% of former smokers: RRadj 1.53 [1.37-1.71]) to receive a Covid-19 vaccine. Conclusions: Current smokers hold more negative attitudes towards vaccines in general, and are more likely to be undecided or unwilling to vaccinate against Covid-19, compared with never and former smokers. With a disproportionately high number of smokers belonging to socially clustered and disadvantaged socioeconomic groups, lower vaccine uptake in this group could also exacerbate health inequalities.
影响因子：
158.5
作者：
Christakis, Nicholas A.;Fowler, James H.
通讯作者：
Fowler, James H.