Clinically Significant Anxiety in Children with Autism Spectrum Disorder and Varied Intellectual Functioning.
Clinically Significant Anxiety in Children with Autism Spectrum Disorder and Varied Intellectual Functioning.
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患有自闭症谱系障碍和智力功能不同的儿童的临床显著焦虑。
DOI：
10.1080/15374416.2019.1703712
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发表时间：
2021-11
影响因子：
4.2
通讯作者：
Amaral, David G.
中科院分区：
文献类型：
--
作者：
Kerns, Connor M.;Winder-Patel, Breanna;Iosif, Ana Maria;Nordahl, Christine Wu;Heath, Brianna;Solomon, Marjorie;Amaral, David G.
To evaluate how distinct presentations of anxiety symptoms and intellectual impairment influence the measurement and estimated rate of clinically significant anxiety in autism spectrum disorder (ASD). The sample included 75 children (ages 9–13 years) with ASD and varied IQ and 52 typically developing (TD) controls and parents. Parents completed anxiety symptom scales and a diagnostic interview, designed to (1) differentiate anxiety and ASD and (2) examine DSM-specified and unspecified (“distinct”) anxiety presentations in each child, including fears of change, special interests, idiosyncratic stimuli and social confusion rather than evaluation. Children completed standard intellectual and ASD diagnostic assessments. 69% of those with ASD had clinically-significant anxiety, including 21% DSM-specified anxiety disorders, 17% distinct anxiety, and 31% both. Only 8% of TD children had clinically-significant anxiety, all DSM-specified. DSM-specified anxiety disorders in children with ASD and intellectual impairment (IQ<70) were predominantly specific phobias. DSM-specified anxiety other than specific phobia was significantly less common in children with, versus without, intellectual impairment; this was not the case for distinct anxiety. The sensitivities of anxiety scales were moderate to poor, particularly in cases with intellectual impairment. ASD is associated with more frequent and varied presentations of clinical anxiety, which may align with and differ from the specified anxiety disorders of the DSM. Standard parent report anxiety scales have reduced sensitivity to detect clinical anxiety in ASD, particularly in children with intellectual impairment.
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影响因子：
3.9
作者：
Gotham, Katherine;Pickles, Andrew;Lord, Catherine
通讯作者：
Lord, Catherine
影响因子：
5.2
作者：
Keen, Deb;Adams, Dawn;Roberts, Jacqueline
通讯作者：
Roberts, Jacqueline
影响因子：
1.7
作者：
Beesdo, Katja;Knappe, Susanne;Pine, Daniel S.
通讯作者：
Pine, Daniel S.
DOI：
10.1016/j.chc.2005.06.003
发表时间：
2005-10-01
影响因子：
2.4
作者：
Costello, EJ;Egger, HL;Angold, A
通讯作者：
Angold, A
影响因子：
2.5
作者：
den Houting, Jacquiline;Adams, Dawn;Keen, Deb
通讯作者：
Keen, Deb