Cross-Activation of the Motor Cortex during Unilateral Contractions of the Quadriceps.
Cross-Activation of the Motor Cortex during Unilateral Contractions of the Quadriceps.
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DOI：
10.3389/fnhum.2017.00397
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发表时间：
2017
影响因子：
2.9
通讯作者：
Teo WP
中科院分区：
文献类型：
--
作者：
Hendy AM;Chye L;Teo WP
经颅磁刺激（TMS）研究表明，上肢的单侧肌肉收缩会在对侧和同侧运动皮层中产生运动皮层活动。激活静息肢体的皮质运动通路的兴奋性增加被称为“交叉激活”，并且由于其参与交叉教育和康复而具有重要性。迄今为止，很少有研究调查了下肢的交叉激活。16名健康受试者（平均年龄29 ± 9岁）参加了本研究。为了确定不同的收缩强度在下肢的影响，我们研究了corticomotor兴奋性和皮质内抑制的右股直肌（RF），而左腿进行等长伸展在0%，25%，50%，75%和100%的最大力输出。收缩强度的50%最大力输出和更大的产生显着的交叉激活的corticomotor通路。在75%和100%收缩期间观察到沉默期持续时间的减少，而仅在最大（100%）收缩期间观察到短间隔皮质内抑制（SICI）的释放。我们的结论是，增加等长收缩强度产生单调增加的交叉激活，这是最大的100%的力输出。因此，旨在诱导下肢力量交叉训练的单侧训练计划应在可耐受的最大强度下进行。
Transcranial magnetic stimulation (TMS) studies have demonstrated that unilateral muscle contractions in the upper limb produce motor cortical activity in both the contralateral and ipsilateral motor cortices. The increase in excitability of the corticomotor pathway activating the resting limb has been termed “cross-activation”, and is of importance due to its involvement in cross-education and rehabilitation. To date, very few studies have investigated cross-activation in the lower limb. Sixteen healthy participants (mean age 29 ± 9 years) took part in this study. To determine the effect of varying contraction intensities in the lower limb, we investigated corticomotor excitability and intracortical inhibition of the right rectus femoris (RF) while the left leg performed isometric extension at 0%, 25%, 50%, 75% and 100% of maximum force output. Contraction intensities of 50% maximal force output and greater produced significant cross-activation of the corticomotor pathway. A reduction in silent period duration was observed during 75% and 100% contractions, while the release of short-interval intracortical inhibition (SICI) was only observed during maximal (100%) contractions. We conclude that increasing isometric contraction intensities produce a monotonic increase in cross-activation, which was greatest during 100% force output. Unilateral training programs designed to induce cross-education of strength in the lower limb should therefore be prescribed at the maximal intensity tolerable.
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DOI：
10.1111/j.1460-9568.2010.07567.x
发表时间：
2011-03
期刊：
The European journal of neuroscience
影响因子：
--
作者：
Howatson G;Taylor MB;Rider P;Motawar BR;McNally MP;Solnik S;DeVita P;Hortobágyi T
通讯作者：
Hortobágyi T
最佳数量的脉冲数量作为神经腔内颅磁刺激的结果度量。
DOI：
10.1016/j.clinph.2016.04.001
发表时间：
2016-08
期刊：
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
影响因子：
--
作者：
Chang WH;Fried PJ;Saxena S;Jannati A;Gomes-Osman J;Kim YH;Pascual-Leone A
通讯作者：
Pascual-Leone A
影响因子：
4.7
作者：
Muellbacher, W;Facchini, S;Hallett, M
通讯作者：
Hallett, M
影响因子：
5.5
作者：
Lee, Hubert;Gunraj, Carolyn;Chen, Robert
通讯作者：
Chen, Robert
影响因子：
5.5
作者：
Avanzino, L.;Teo, J. T. H.;Rothwell, J. C.
通讯作者：
Rothwell, J. C.