Silicone wristbands as personal passive samplers.
Silicone wristbands as personal passive samplers.
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DOI：
10.1021/es405022f
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发表时间：
2014-03-18
影响因子：
11.4
通讯作者：
Anderson, Kim A.
中科院分区：
文献类型：
--
作者：
O'Connell, Steven G.;Kind, Laurel D.;Anderson, Kim A.
主动采样方法通常用于个人监测，但受到能源使用和可能不代表个人接触或生物可利用浓度的数据的限制。目前的被动技术通常涉及广泛的制备，或仅针对少量目标化合物开发。在这项工作中，我们提出了一种新的应用程序，用于测量生物可利用的暴露与硅胶腕带作为个人被动采样器。采用市售硅胶开发了影响预清洗、输注和浸提的实验室方法，溶剂净化后色谱背景干扰减少，浸提效率良好（>96%）。在最后确定实验室方法后，49种化合物在环境部署期间被隔离，其中包括多环芳烃（PAH），消费品，个人护理产品，农药，邻苯二甲酸酯和其他工业化合物，其辛醇/水分配系数从-0.07（咖啡因）到9.49（磷酸三（2-乙基己基）酯）不等。在两个热沥青职业环境中，硅胶个人采样器在8小时和40小时暴露期间隔离了25种多环芳烃，以及2种氧化多环芳烃（苯并芴酮和芴酮），表明在一个工作日或一周内的时间敏感性（p < 0.05，功效=0.85）。此外，不同工作地点的PAH隔离量不同（p < 0.05，功效= 0.99），表明使用这种新应用的空间敏感性。
Active-sampling approaches are commonly used for personal monitoring, but are limited by energy usage and data that may not represent an individual’s exposure or bioavailable concentrations. Current passive techniques often involve extensive preparation, or are developed for only a small number of targeted compounds. In this work, we present a novel application for measuring bioavailable exposure with silicone wristbands as personal passive samplers. Laboratory methodology affecting precleaning, infusion, and extraction were developed from commercially available silicone, and chromatographic background interference was reduced after solvent cleanup with good extraction efficiency (>96%). After finalizing laboratory methods, 49 compounds were sequestered during an ambient deployment which encompassed a diverse set of compounds including polycyclic aromatic hydrocarbons (PAHs), consumer products, personal care products, pesticides, phthalates, and other industrial compounds ranging in log Kow from −0.07 (caffeine) to 9.49 (tris(2-ethylhexyl) phosphate). In two hot asphalt occupational settings, silicone personal samplers sequestered 25 PAHs during 8- and 40-h exposures, as well as 2 oxygenated-PAHs (benzofluorenone and fluorenone) suggesting temporal sensitivity over a single work day or week (p < 0.05, power =0.85). Additionally, the amount of PAH sequestered differed between worksites (p < 0.05, power = 0.99), suggesting spatial sensitivity using this novel application.
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影响因子：
11.4
作者：
Allan, Sarah E.;Smith, Brian W.;Anderson, Kim A.
通讯作者：
Anderson, Kim A.
影响因子：
4.1
作者：
Allan, Ian J.;Harman, Christopher;Grung, Merete
通讯作者：
Grung, Merete
影响因子：
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作者：
Foreman, WT;Majewski, MS;Coupe, RH
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Coupe, RH
影响因子：
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作者：
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通讯作者：
Wise, Stephen A.
影响因子：
10.4
作者：
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通讯作者：
Spink DC