Genome Context Viewer: visual exploration of multiple annotated genomes using microsynteny.

Genome Context Viewer: visual exploration of multiple annotated genomes using microsynteny.
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DOI:
10.1093/bioinformatics/btx757
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发表时间:
2018-05-01
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
通讯作者:
Farmer A
Farmer A
中科院分区:
其他
文献类型:
--
作者:
Cleary A;Farmer A

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基因组上下文查看器是一种可视化数据挖掘工具,允许用户在多个基因组数据提供者之间搜索具有类似注释内容的区域,这些区域可以在其共享功能元素的水平上对齐和可视化。通过将基因家族成员的有序序列作为搜索和比较的单元来处理,用户界面使得能够快速且直观地评估基因内容分歧的程度以及同线背景内各种类型的结构事件的存在。深入了解在这个抽象层次上看到的功能上的显著差异,可以指导用户在其他互连的、特定于提供商的工具中对底层数据进行更详细的探索。 GCV在GNU通用公共许可证第3版(GPL-3.0)下提供。源代码可在https://github.com/legumeinfo/lis_context_viewer上获得。 补充数据可在Bioinformatics在线获得。
The Genome Context Viewer is a visual data-mining tool that allows users to search across multiple providers of genome data for regions with similarly annotated content that may be aligned and visualized at the level of their shared functional elements. By handling ordered sequences of gene family memberships as a unit of search and comparison, the user interface enables quick and intuitive assessment of the degree of gene content divergence and the presence of various types of structural events within syntenic contexts. Insights into functionally significant differences seen at this level of abstraction can then serve to direct the user to more detailed explorations of the underlying data in other interconnected, provider-specific tools. GCV is provided under the GNU General Public License version 3 (GPL-3.0). Source code is available at https://github.com/legumeinfo/lis_context_viewer. Supplementary data are available at Bioinformatics online.
DOI: 10.1093/nar/gkv1159
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影响因子: 14.9
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