Pre-pregnancy potato consumption and risk of gestational diabetes mellitus: prospective cohort study.
Pre-pregnancy potato consumption and risk of gestational diabetes mellitus: prospective cohort study.
复制标题
DOI：
10.1136/bmj.h6898
复制
发表时间：
2016-01-12
期刊：
影响因子：
--
通讯作者：
Zhang C
中科院分区：
文献类型：
--
作者：
Bao W;Tobias DK;Hu FB;Chavarro JE;Zhang C
研究问题：怀孕前食用土豆与妊娠期糖尿病（GDM）风险之间有何关联？方法前瞻性队列研究纳入1991-2001年护士健康研究II的15632名妇女。她们在怀孕前没有GDM或慢性疾病。土豆和其他食物的消耗量每四年评估一次。事件第一次GDM是确定从自述的医生诊断的GDM，这是以前的医疗记录验证。在10年的随访中，21 693例单胎妊娠中有854例发生GDM。在调整了年龄、胎次、饮食和非饮食因素后，怀孕前食用更多土豆的女性患GDM的几率更高。用其他蔬菜、豆类和全谷物食物代替每周两次的土豆，与GDM风险降低9-12%显著相关。饮酒量和糖尿病都是自我报告，糖尿病的严重程度是未知的。超过90%的女性是白人。不能假定有因果关系。怀孕前吃更多的土豆会增加患GDM的风险，用其他蔬菜、豆类或全谷物食物代替土豆可能会降低风险。资助、利益竞争、数据共享资金来自Eunice Kennedy Shriver国家儿童健康与人类发展研究所、美国国立卫生研究院和美国糖尿病协会的校内研究项目（No . 7-12 mn -34）。作者没有竞争利益，也没有额外的数据要分享。
Study question What is the association between potato consumption before pregnancy and the risk of gestational diabetes mellitus (GDM)? Methods This prospective cohort study included 15 632 women from the Nurses’ Health Study II (1991-2001). They had no previous GDM or chronic diseases before pregnancy. Consumption of potatoes and other foods was assessed every four years. Incident first time GDM was ascertained from self reports of a physician diagnosis of GDM, which was previously validated by medical records. Study answer and limitations Over the 10 year follow-up there were 854 incident cases of GDM among 21 693 singleton pregnancies. After adjustment for age, parity, and dietary and non-dietary factors, women who consumed more potatoes before pregnancy had higher rates of developing GDM. Substitution of two servings a week of total potatoes with other vegetables, legumes, and whole grain foods was significantly associated with a 9-12% lower risk of GDM. Consumption and diabetes were self reported, and severity of diabetes was unknown. More than 90% of women were white. A causal association cannot be assumed. What this paper adds Higher levels of potato consumption before pregnancy are associated with greater risk of GDM, and substitution of potatoes with other vegetables, legumes, or whole grain foods might lower the risk. Funding, competing interests, data sharing Funding was received from the Intramural Research Program of the Eunice Kennedy Shriver National Institute of Child Health and Human Development, the National Institutes of Health, and the American Diabetes Association (No 7-12-MN-34). The authors have no competing interests or additional data to share.
登录
查看更多内容
影响因子：
--
作者：
Goldberg, T;Cai, WJ;Vlassara, H
通讯作者：
Vlassara, H
影响因子：
16.2
作者：
Liu, SM;Serdula, M;Buring, JE
通讯作者：
Buring, JE
影响因子：
16.2
作者：
Ferrara, A;Hedderson, MM;Selby, JV
通讯作者：
Selby, JV
影响因子：
--
作者：
Pan, An;Sun, Qi;Bernstein, Adam M.;Schulze, Matthias B.;Manson, JoAnn E.;Stampfer, Meir J.;Willett, Walter C.;Hu, Frank B.
通讯作者：
Hu, Frank B.
DOI：
10.1056/nejmoa1014296
发表时间：
2011-06-23
期刊：
The New England journal of medicine
影响因子：
--
作者：
Mozaffarian D;Hao T;Rimm EB;Willett WC;Hu FB
通讯作者：
Hu FB