The role of mood disorders in the progression of and recovery from alcohol and drug use problems: A latent transition analysis.
The role of mood disorders in the progression of and recovery from alcohol and drug use problems: A latent transition analysis.
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DOI：
10.1016/j.drugalcdep.2022.109566
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发表时间：
2022-09-01
影响因子：
4.2
通讯作者：
Reboussin, Beth A.
中科院分区：
文献类型：
--
作者：
Crum, Rosa M.;Green, Kerry M.;Amin-Esmaeili, Masoumeh;Susukida, Ryoko;Mojtabai, Ramin;Storr, Carla L.;Riehm, Kira E.;Young, Andrea S.;Reboussin, Beth A.
关键词：
评估情绪障碍是否能预测物质使用行为的纵向研究有限。我们扩展了我们之前的工作，评估了酒精使用的过渡模式，以评估酒精和药物使用问题的模式。利用全国酒精及相关疾病流行病学调查的前瞻性数据，第1波和第2波，我们完成了潜在类别分析，根据DSM障碍标准经验地定义了酒精和毒品问题的类别。潜伏期转换分析被用来评估基线时终生情绪障碍与随访期间酒精和药物问题类别转换的相关性。为男性和女性确定了酒精和毒品问题的三类模型(无问题、只有酒精问题和酒精和毒品问题)。与无情绪障碍的女性相比，有情绪障碍的女性从无问题和仅有酒精问题过渡到在随访时有酒精和药物问题的可能性是无情绪障碍女性的两倍多(AOR=2.3，95%CI=1.31-4.05，p=0.004；AOR=2.64，CI=1.24-5.62，p=0.011)。此外，与没有情绪障碍的女性相比，有情绪障碍的女性仅在随访时才能从基线的酒精和药物问题恢复到酒精问题的可能性显著降低(AOR=0.35，CI=0.12-0.98，p=0.047)。对于男性来说，没有显著的发现。我们的研究提供了证据，证明情绪障碍会通过酒精和药物问题影响女性的转变。研究结果强调，需要对有情绪问题的人进行持续的物质使用评估，并在那些从物质使用问题中恢复的人中识别和治疗情绪障碍。
Longitudinal research assessing whether mood disorders predict substance use behaviors is limited. We extend our prior work evaluating transition patterns with alcohol use to assess patterns with alcohol and drug use problems. Using National Epidemiologic Survey on Alcohol and Related Conditions prospective data, waves 1 and 2, we completed latent class analyses to empirically define classes of alcohol and drug problems from DSM disorder criteria. Latent transition analyses were used to assess associations of lifetime mood disorders at baseline with transitions across classes of alcohol and drug problems during follow-up. A three-class model of alcohol and drug problems was identified (No problems, Alcohol Problems Only, and Alcohol and Drug Problems) for males and females. Females with mood disorders were over two times more likely to transition from No Problems, and Alcohol Problems Only at baseline to having both Alcohol and Drug Problems at follow-up relative to those without mood disorders (aOR=2.30, 95 % CI=1.31–4.05, p = 0.004, and aOR=2.64, CI=1.24–5.62, p = 0.011, respectively). Furthermore, females with mood disorders were significantly less likely to recover from baseline Alcohol and Drug Problems to Alcohol Problems Only at follow-up (aOR=0.35, CI=0.12–0.98, p = 0.047) relative to those without mood disorders. There were no significant findings for males. Our study provides evidence that mood disorders impact transitions through classes of alcohol and drug problems among females. The findings emphasize the need for ongoing evaluation of substance use among those with mood conditions, and recognition and treatment of mood disorders among those recovering from substance use problems.
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