A mouse homeo box gene is expressed in spermatocytes and embryos.
A mouse homeo box gene is expressed in spermatocytes and embryos.
复制标题
小鼠同源盒基因在精母细胞和胚胎中表达。
作者：
M. Rubin;L. E. Toth;M. Patel;P. D’Eustachio;M. Nguyen
MH-3基因含有一个在成年睾丸中特异表达的同源盒，已被鉴定并定位于小鼠6号染色体。通过与成年小鼠睾丸组织的原位杂交和与青春期前小鼠和Sl/Sld突变小鼠睾丸RNA的北方印迹杂交，证实该基因在减数分裂晚期的雄性生殖细胞中表达。在胚胎中，MH-3转录本出现在交配后第11.5天，这是小鼠发育中性腺分化尚未发生的阶段。MH-3基因可能在精子发生和胚胎发生中起作用。
The MH-3 gene, which contains a homeo box that is expressed specifically in the adult testis, was identified and mapped to mouse chromosome 6. By means of in situ hybridization with adult testis sections and Northern blot hybridization with testis RNA from prepuberal mice and from Sl/Sld mutant mice, it was demonstrated that this gene is expressed in male germ cells during late meiosis. In the embryo, MH-3 transcripts were present at day 11.5 post coitum, a stage in mouse development when gonadal differentiation has not yet occurred. The MH-3 gene may have functions in spermatogenesis and embryogenesis.
影响因子：
2.7
作者：
COX, KH;DELEON, DV;ANGERER, RC
通讯作者：
ANGERER, RC
编码小鼠神经细胞粘附分子 (N-CAM) 的基因的染色体位置。
DOI：
10.1073/pnas.82.22.7631
发表时间：
1985
影响因子：
11.1
作者：
D'Eustachio,P;Owens,GC;Edelman,GM;Cunningham,BA
通讯作者：
Cunningham,BA